(S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine

Base Information

• Chemical Name: (S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine
• CAS No.: 440634-07-1
• Molecular Formula: C₁₅H₂₂N₂O₄S
• Molecular Weight: 326.417
• Mol file: 440634-07-1.mol

Synonyms:(S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine

Chemical Property of (S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine

There total 3 articles about (S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-S-(5-methyl-2-nitrophenyl)-N-(tert-butyloxycarbonyl)cysteine (440634-02-6) → (S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine (440634-07-1)

Guidance literature:

With ammonium chloride; zinc; In methanol; at 20 - 75 ℃; for 4h;

DOI:10.1080/00304940209458076

Reference yield:

2-fluoro-4-methyl-1-nitrobenzene (446-34-4) → (S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine (440634-07-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / sodium hydrogen carbonate / ethanol; H₂O / 6 h / Heating

2: 100 percent / zinc; ammonium chloride / methanol / 4 h / 20 - 75 °C

With ammonium chloride; sodium hydrogencarbonate; zinc; In methanol; ethanol; water;

DOI:10.1080/00304940209458076

Reference yield:

(S)-N-(tert-butyloxycarbonyl)cysteine → (S)-S-(5-methyl-2-aminophenyl)-N-(tert-butyloxycarbonyl)cysteine (440634-07-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / sodium hydrogen carbonate / ethanol; H₂O / 6 h / Heating

2: 100 percent / zinc; ammonium chloride / methanol / 4 h / 20 - 75 °C

With ammonium chloride; sodium hydrogencarbonate; zinc; In methanol; ethanol; water;

DOI:10.1080/00304940209458076

upstream raw materials:

(S)-S-(5-methyl-2-nitrophenyl)-N-(tert-butyloxycarbonyl)cysteine

2-fluoro-4-methyl-1-nitrobenzene