Technology Process of 2,6-bis(1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)pyridine
There total 1 articles about 2,6-bis(1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)pyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-bromo-4-methoxy-benzene;
With
copper(l) iodide; sodium azide; sodium L-ascorbate; N,N`-dimethylethylenediamine;
In
ethanol; water;
at 20 ℃;
for 2.5h;
Inert atmosphere;
Reflux;
2,6-diethynylpyridine;
With
sodium L-ascorbate;
In
ethanol; water;
at 20 ℃;
for 16h;
Inert atmosphere;
Reflux;
DOI:10.1039/b813925c
- Guidance literature:
-
With
catalyst: N-ethylmorpholine;
In
methanol;
to a suspn. of Ru-contg. compd. (1 equiv.) and a ligand (1 equiv.) in MeOH N-ethylmorpholine (10 drops) was added; the react. mixt. was stirred under reflux for 24 h; the mixt. was filtered hot and then an excess of NH4PF6 was added; stirring for 30 min; H2O was added and ppt. was filtered off, washed with H2O; ppt. was dissolved in CH2Cl2, soln. was evapd. after drying over Na2SO4; recrystn. from CH3CN-Et2O; column chromy. (silica, CH3CN-H2O 9:1, satd. with KNO3); elem. anal.;
DOI:10.1039/b813925c
