C₆₇H₈₇NO₇

Base Information

• Chemical Name: C₆₇H₈₇NO₇
• CAS No.: 1558035-11-2
• Molecular Formula: C₆₇H₈₇NO₇
• Molecular Weight: 1018.43
• Mol file: 1558035-11-2.mol

Synonyms:C₆₇H₈₇NO₇

Chemical Property of C₆₇H₈₇NO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₇H₈₇NO₇

There total 24 articles about C₆₇H₈₇NO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C68H85NO8 (1558035-10-1) → C67H87NO7 (1558035-11-2)

Guidance literature:

With water; potassium hydroxide; In tetrahydrofuran; ethanol; at 125 ℃; for 6h; Inert atmosphere; Sealed tube;

DOI:10.1021/ol5002686

Reference yield:

(4R,5R)-2,2-Dimethyl-5-tetradecyl-[1,3]dioxolane-4-carbaldehyde (1027896-10-1) → C67H87NO7 (1558035-11-2)

Guidance literature:

Multi-step reaction with 11 steps

1.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

1.2: 2 h / 0 - 20 °C / Inert atmosphere

2.1: acetyl chloride / methanol / 0.5 h / Inert atmosphere

3.1: toluene-4-sulfonic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere

4.1: diisobutylaluminium hydride / dichloromethane; hexane / 3.5 h / -78 - 20 °C / Inert atmosphere

5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C / Inert atmosphere

5.2: 3 h / 0 - 20 °C / Inert atmosphere

6.1: sodium hydrogencarbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 0.42 h / 20 °C / Inert atmosphere

7.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 16 h / 40 °C / Inert atmosphere

8.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

8.2: 3 h / 20 °C / Inert atmosphere

8.3: 1 h / 20 °C / Inert atmosphere

9.1: iodonium dicollidine perchlorate / dichloromethane / 16 h / 20 °C / Inert atmosphere

10.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / benzene / 1 h / 80 °C / Inert atmosphere

11.1: potassium hydroxide; water / tetrahydrofuran; ethanol / 6 h / 125 °C / Inert atmosphere; Sealed tube

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; 2,2'-azobis(isobutyronitrile); potassium tert-butylate; water; tri-n-butyl-tin hydride; sodium hydride; diisobutylaluminium hydride; sodium hydrogencarbonate; toluene-4-sulfonic acid; acetyl chloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; potassium hydroxide; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; mineral oil; benzene;

DOI:10.1021/ol5002686

Reference yield:

(3S,4S)-3,4-O-isopropylideneoctadec-1-ene-3,4-diol (175435-56-0) → C67H87NO7 (1558035-11-2)

Guidance literature:

Multi-step reaction with 10 steps

1.1: acetyl chloride / methanol / 0.5 h / Inert atmosphere

2.1: toluene-4-sulfonic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / dichloromethane; hexane / 3.5 h / -78 - 20 °C / Inert atmosphere

4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C / Inert atmosphere

4.2: 3 h / 0 - 20 °C / Inert atmosphere

5.1: sodium hydrogencarbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 0.42 h / 20 °C / Inert atmosphere

6.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 16 h / 40 °C / Inert atmosphere

7.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

7.2: 3 h / 20 °C / Inert atmosphere

7.3: 1 h / 20 °C / Inert atmosphere

8.1: iodonium dicollidine perchlorate / dichloromethane / 16 h / 20 °C / Inert atmosphere

9.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / benzene / 1 h / 80 °C / Inert atmosphere

10.1: potassium hydroxide; water / tetrahydrofuran; ethanol / 6 h / 125 °C / Inert atmosphere; Sealed tube

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; 2,2'-azobis(isobutyronitrile); water; tri-n-butyl-tin hydride; sodium hydride; diisobutylaluminium hydride; sodium hydrogencarbonate; toluene-4-sulfonic acid; acetyl chloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; potassium hydroxide; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; mineral oil; benzene;

DOI:10.1021/ol5002686

upstream raw materials:

1-(3',4',6'-tri-O-benzyl-α-D-galactopyranosyl)-2-propene

C₃₈H₃₈O₈

C₆₄H₈₀O₁₀

C₆₂H₇₆O₁₀