[3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride

Base Information

Chemical Name:[3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride
CAS No.:85257-71-2
Molecular Formula:C₂₆H₃₂Br₂N₂O₂*ClH
Molecular Weight:600.821
Hs Code.:

Synonyms:[3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride

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Chemical Property of [3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride

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Technology Process of [3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride

There total 3 articles about [3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.9%

: 39743-36-7
1-chloro-3-(dipropylamino)propane

: 77823-56-4
2-ethyl-3-(3,5-dibromo-4-hydroxy-benzoyl)-indolizine

: 85257-71-2
[3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride

Guidance literature:: With potassium carbonate; In acetone; for 20h; Heating;

Reference yield:

: 3337-62-0
3,5-dibromo-4-hydroxybenzoic acid

: 85257-71-2
[3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / thionyl chloride / dimethylformamide / 2 h / Ambient temperature

2: 47.2 percent / 1,2-dichloro-ethane / 40 h / Ambient temperature

3: 49.9 percent / potassium carbonate / acetone / 20 h / Heating

With thionyl chloride; potassium carbonate; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetone;

Reference yield:

: 77823-55-3
3,5-dibromo-4-hydroxy-benzoyl chloride

: 85257-71-2
[3,5-Dibromo-4-(3-dipropylamino-propoxy)-phenyl]-(2-ethyl-indolizin-3-yl)-methanone; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 47.2 percent / 1,2-dichloro-ethane / 40 h / Ambient temperature

2: 49.9 percent / potassium carbonate / acetone / 20 h / Heating

With potassium carbonate; In 1,2-dichloro-ethane; acetone;