N₁-[1-[N-[(S)-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarbonyl]-L-prolinamide

Base Information

• Chemical Name: N₁-[1-[N-[(S)-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarbonyl]-L-prolinamide
• CAS No.: 236123-27-6
• Molecular Formula: C₁₆H₂₄N₄O₄
• Molecular Weight: 336.391

Synonyms:N₁-[1-[N-[(S)-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarbonyl]-L-prolinamide

Chemical Property of N₁-[1-[N-[(S)-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarbonyl]-L-prolinamide

Chemical Property:

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Technology Process of N₁-[1-[N-[(S)-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarbonyl]-L-prolinamide

There total 1 articles about N₁-[1-[N-[(S)-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarbonyl]-L-prolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

[(S)-1-[N-tert-butyldimethylsilyl-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarboxylic acid (236123-26-5) + L-prolinamide (7531-52-4) → N1-[1-[N-[(S)-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarbonyl]-L-prolinamide (236123-27-6)

Guidance literature:

[(S)-1-[N-tert-butyldimethylsilyl-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarboxylic acid; With 2,3,4,5,6-pentafluorophenol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 0 ℃; for 1.5h;

L-prolinamide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

upstream raw materials:

[(S)-1-[N-tert-butyldimethylsilyl-4-oxo-azetidine-2-carbonyl]amino]cyclohexanecarboxylic acid

L-prolinamide

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