2--1-(phenylsulfonyl)indole

Base Information

• Chemical Name: 2--1-(phenylsulfonyl)indole
• CAS No.: 128721-36-8
• Molecular Formula: C₁₉H₂₁NO₃S₃
• Molecular Weight: 407.579

Synonyms:2--1-(phenylsulfonyl)indole

Chemical Property of 2--1-(phenylsulfonyl)indole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2--1-(phenylsulfonyl)indole

There total 2 articles about 2--1-(phenylsulfonyl)indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-bis(ethylthiomethyl)-1-phenylsulfonylindole (128721-28-8) → 2--1-(phenylsulfonyl)indole (128721-36-8)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; at 0 ℃; for 5h;

DOI:10.3987/COM-89-5240

Reference yield:

1-(phenylsulfonyl)-1H-indole-2-carbaldehyde (80360-23-2) → 2--1-(phenylsulfonyl)indole (128721-36-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / p-toluenesulfonic acid / toluene / 15 h / Ambient temperature

2: 84 percent / 85percent MCPBA / CH₂Cl₂; H₂O / 5 h / 0 °C

With toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; toluene;

DOI:10.3987/COM-89-5240

Reference yield:

1-Methyl-4-piperidone (1445-73-4) + 2--1-(phenylsulfonyl)indole (128721-36-8) → 4-<1-ethylthio-1-(1-phenylsulfonyl-2-indolyl)methyl>-1-methyl-4-piperidinol (128721-34-6) + 4-[(1-Benzenesulfonyl-1H-indol-2-yl)-ethanesulfinyl-methyl]-1-methyl-piperidin-4-ol (128721-37-9)

Guidance literature:

With n-butyllithium; Multistep reaction; 1.) THF, -20 deg C, 1 h, 2.) 1 h;

DOI:10.3987/COM-89-5240

upstream raw materials:

2-bis(ethylthiomethyl)-1-phenylsulfonylindole

1-(phenylsulfonyl)-1H-indole-2-carbaldehyde

Downstream raw materials:

4-<1-ethylthio-1-(1-phenylsulfonyl-2-indolyl)methyl>-1-methyl-4-piperidinol

4-[(1-Benzenesulfonyl-1H-indol-2-yl)-ethanesulfinyl-methyl]-1-methyl-piperidin-4-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 128721-36-8 2--1-(phenylsulfonyl)indole

Send

Send

Metric Ton KG G Pound L ML

Send

Send