(1R,5S)-5-amino-3-methylcyclopent-2-ene-1-carboxylic acid

Base Information

Chemical Name:(1R,5S)-5-amino-3-methylcyclopent-2-ene-1-carboxylic acid
CAS No.:156292-40-9
Molecular Formula:C₇H₁₁NO₂
Molecular Weight:141.17
Hs Code.:
ChEMBL ID:CHEMBL1193639
DSSTox Substance ID:DTXSID20414988
Nikkaji Number:J1.876.298F
Wikidata:Q82224097
Mol file:156292-40-9.mol

Synonyms:(1R,5S)-5-amino-3-methylcyclopent-2-ene-1-carboxylic acid;156292-40-9;2-Cyclopentene-1-carboxylicacid,5-amino-3-methyl-,cis-(9CI);AC1NQNA5;CHEMBL1193639;DTXSID20414988;AKOS006364332;(1R,5S)-5-amino-3-methyl-cyclopent-2-ene-1-carboxylic acid;2-Cyclopentene-1-carboxylic acid, 5-amino-3-methyl-, (1R,5S)-

Suppliers and Price of (1R,5S)-5-amino-3-methylcyclopent-2-ene-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (1R,5S)-5-amino-3-methylcyclopent-2-ene-1-carboxylic acid

Chemical Property:

PSA：63.32000
LogP:1.06480
XLogP3:-2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:141.078978594
Heavy Atom Count:10
Complexity:186

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(C(C1)N)C(=O)O
Isomeric SMILES:CC1=C[C@H]([C@H](C1)N)C(=O)O

Technology Process of (1R,5S)-5-amino-3-methylcyclopent-2-ene-1-carboxylic acid

There total 13 articles about (1R,5S)-5-amino-3-methylcyclopent-2-ene-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 939962-93-3
(+)-(1S,5S)-3-methyl-5-(3-phenyl-allyloxycarbonylamino)-cyclopent-2-enecarboxylic acid

: 156292-40-9
(+)-(1S,5S)-5-amino-3-methyl-cyclopent-2-enecarboxylic acid

Guidance literature:: With morpholine; triphenylphosphine; palladium diacetate; In ethanol; for 2h; Heating;
DOI:10.1016/j.tetasy.2007.02.019

Reference yield:

: 939962-91-1
(-)-(1R,5S)-3-methyl-5-(3-phenyl-allyloxycarbonylamino)-cyclopent-2-enecarboxylic acid 3-phenyl-allyl ester

: 156292-40-9
(-)-(1R,5S)-5-amino-3-methyl-cyclopent-2-enecarboxylic acid

Guidance literature:: With morpholine; triphenylphosphine; palladium diacetate; In ethanol; for 2h; Heating;
DOI:10.1016/j.tetasy.2007.02.019

Reference yield:

: 5-methyl-4,6a-dihydro-3aH-cyclopenta[c]furan-1,3-dione

: 156292-40-9
(+)-(1S,5S)-5-amino-3-methyl-cyclopent-2-enecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: quinine / toluene / 8 h / -15 °C

1.2: diphenyl phosphoryl azide; triethylamine / toluene / 3 h / 20 - 90 °C

1.3: 9.0 g / toluene / Heating

2.1: 75 percent / potassium hydroxide / methanol; H₂O / 2 h / 50 °C

3.1: 62 percent / morpholine; triphenyl phosphine / palladium(II) acetate / ethanol / 2 h / Heating

With morpholine; potassium hydroxide; triphenylphosphine; Quinine; palladium diacetate; In methanol; ethanol; water; toluene; 1.2: Curtius rearrangement;
DOI:10.1016/j.tetasy.2007.02.019