Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN

Base Information

• Chemical Name: Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN
• CAS No.: 156192-32-4
• Molecular Formula: C30H38 N6 O6
• Molecular Weight: 578.66
• Mol file: 156192-32-4.mol

Synonyms:Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN;Z-LEU-ARG-AMC;Z-LEU-ARG-AMC HYDROCHLORIDE

Chemical Property of Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN

Chemical Property:

• PSA: 188.64000
• LogP: 5.17480
• Storage Temp.: Store at 0-5°C
• Solubility.: Soluble in DMSO

Purity/Quality:

99%+, ^*data from raw suppliers

Z-Leu-Arg-AMC·HCl,99% 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: Z-Leu-Arg-AMC (156192-32-4) is a sensitive Cathepsin K fluorogenic substrate (Km=8μM, kcat/Km=4 x 105 M-1s-1)1-3. It is cleaved more slowly by the following cathepsins (kcat/Km: B (105)4, F (106)4, L (106)4,5, L2/V (104)5, S (105)2,4,5. Also cleaved by malaria parasite proteases berghepain6, vivapain-2 and -37, and falcipain-1, -2, and -36,8,9. Excitation: 365nm, Emission: 440nm.
• Uses: A sensitive fluorogenic substrate for cathepsin K