Chemical Property of Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN
Chemical Property:
- PSA:188.64000
- LogP:5.17480
- Storage Temp.:Store at 0-5°C
- Solubility.:Soluble in DMSO
- Purity/Quality:
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99% *data from raw suppliers
Z-Leu-Arg-AMC·HCl,99% 99% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
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Description
Z-Leu-Arg-AMC (156192-32-4) is a sensitive Cathepsin K fluorogenic substrate (Km=8μM, kcat/Km=4 x 105 M-1s-1)1-3. It is cleaved more slowly by the following cathepsins (kcat/Km: B (105)4, F (106)4, L (106)4,5, L2/V (104)5, S (105)2,4,5. Also cleaved by malaria parasite proteases berghepain6, vivapain-2 and -37, and falcipain-1, -2, and -36,8,9. Excitation: 365nm, Emission: 440nm.
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Uses
A sensitive fluorogenic substrate for cathepsin K