2,5-Dimethylfuran-3-carbaldehyde

Base Information

• Chemical Name: 2,5-Dimethylfuran-3-carbaldehyde
• CAS No.: 54583-69-6
• Molecular Formula: C₇H₈O₂
• Molecular Weight: 124.139
• European Community (EC) Number: 840-546-4
• Mol file: 54583-69-6.mol

Synonyms:2,5-dimethylfuran-3-carbaldehyde;54583-69-6;SCHEMBL766908;RIMWBHRVGAHGNE-UHFFFAOYSA-N;AKOS003934010;AT17481;CS-0308540;2,5-dimethylfuran-3-carboxaldehyde, AldrichCPR;EN300-123805;Z57500361;F2148-0238

Chemical Property of 2,5-Dimethylfuran-3-carbaldehyde

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 124.052429494
• Heavy Atom Count: 9
• Complexity: 112

Purity/Quality:

99% ^*data from raw suppliers

2,5-dimethylfuran-3-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(O1)C)C=O

Technology Process of 2,5-Dimethylfuran-3-carbaldehyde

There total 10 articles about 2,5-Dimethylfuran-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

propionaldehyde (123-38-6) + methyl vinyl ketone (78-94-4,25038-87-3) → dimethyl-2,5 formyl-3 furanne (54583-69-6)

Guidance literature:

With oxygen; acetic acid; palladium diacetate; cerium(III) chloride; In methanol; at 60 ℃; for 3.5h; under 760.051 Torr;

DOI:10.1021/jo701635f

Reference yield: 70.0%

2,5-Dimethyl-N-phenyl-furan-3-carboximidoyl chloride (79190-42-4) → dimethyl-2,5 formyl-3 furanne (54583-69-6)

Guidance literature:

With hydrogenchloride; chlorure stanneaux; In diethyl ether; at 20 ℃; for 18h;

Reference yield: 60.0%

2,5-hexanedione (110-13-4) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → dimethyl-2,5 formyl-3 furanne (54583-69-6)

Guidance literature:

With trichlorophosphate; a) RT, 1 h, b) 80 deg C, 4 h;

DOI:10.1080/00397919308012593

upstream raw materials:

2,5-Dimethyl-N-phenyl-furan-3-carboximidoyl chloride

2,5-hexanedione

N,N-dimethyl-formamide

2-methyl-furan-3-carboxaldehyde

Downstream raw materials:

cyclohexyl(2,5-dimethylfuran-3-yl)methanol