scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl]

Base Information

• Chemical Name: scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl]
• CAS No.: 1011725-65-7
• Molecular Formula: C₂₈H₄₀N₄O₆
• Molecular Weight: 528.649
• Mol file: 1011725-65-7.mol

Synonyms:scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl]

Chemical Property of scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl]

There total 10 articles about scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C28H42N4O6 (1011725-85-1) → scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl] (1011725-65-7)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 25 ℃; for 3h;

DOI:10.1007/s00726-011-0947-6

Reference yield:

cyclo(-L-Ae9-Aib-L-Phe-D-Pro-) (887277-64-7) → scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl] (1011725-65-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 18.5 h / 20 °C / Cooling

2: methanol / 16 h / 28 °C

3: Dess-Martin periodane / dichloromethane / 3 h / 25 °C

With Dess-Martin periodane; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane;

DOI:10.1007/s00726-011-0947-6

Reference yield:

cyclo(-L-Ae9(epo)-Aib-L-Phe-D-Pro-) (887277-65-8) → scyclo [L-2-amino-8-oxoundecanoyl-aminoisobutyryl-L-phenylalanyl-D-prolyl] (1011725-65-7)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 16 h / 28 °C

2: Dess-Martin periodane / dichloromethane / 3 h / 25 °C

With Dess-Martin periodane; In methanol; dichloromethane;

DOI:10.1007/s00726-011-0947-6

upstream raw materials:

cyclo(-L-Ae₉-Aib-L-Phe-D-Pro-)

cyclo(-L-Ae₉(epo)-Aib-L-Phe-D-Pro-)

Boc-L-Ae₉-Aib-L-Phe-D-Pro-OtBu

C₂₈H₄₂N₄O₆