3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine

Base Information

Chemical Name:3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine
CAS No.:155789-84-7
Molecular Formula:C₈H₁₀N₄
Molecular Weight:162.194
Hs Code.:
DSSTox Substance ID:DTXSID00438480
Wikidata:Q82254240
Mol file:155789-84-7.mol

Synonyms:155789-84-7;3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine;3,6-DIMETHYLIMIDAZO[4,5-B]PYRIDIN-2-AMINE;3H-Imidazo[4,5-b]pyridin-2-amine, 3,6-dimethyl-;2-Amino-3,6-dimethylimidazo[4,5-b]pyridine;DTXSID00438480;AKOS017529852

Suppliers and Price of 3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine
10mg
$ 160.00

AccelPharmtech
3,6-dimethyl-3H-Imidazo[4,5-b]pyridin-2-amine 97.00%
25G
$ 12900.00

AccelPharmtech
3,6-dimethyl-3H-Imidazo[4,5-b]pyridin-2-amine 97.00%
1G
$ 3960.00

Total 1 raw suppliers

Chemical Property of 3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine

Chemical Property:

Boiling Point:366.4±34.0 °C(Predicted)
PKA:8.12±0.30(Predicted)
PSA：57.46000
Density:1.35±0.1 g/cm3(Predicted)
LogP:0.78900
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:162.090546336
Heavy Atom Count:12
Complexity:172

Purity/Quality:: 3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(N=C1)N(C(=N2)N)C
Uses 3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine possesses anti-bacterial properties in various body organs of cockroaches (Periplaneta americana) and showed potent anti-bacterial activity in crude brain against methicillin-resistant Staphylococcus aureus and neuropathogenic Escherichia coli K1.

Technology Process of 3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine

There total 7 articles about 3,6-Dimethyl-3H-imidazo[4,5-b]pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 155790-11-7
2-chloro-3,6-dimethylimidazo<4,5-b>pyridine

: 155789-84-7
2-amino-3,6-dimethylimidazo<4,5-b>pyridine

Guidance literature:: With ammonium hydroxide; at 100 ℃;

Reference yield:

: 1603-41-4
(5-methyl-pyridin-2-yl)amine

: 155789-84-7
2-amino-3,6-dimethylimidazo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 7 steps

1: ethanol / 5 h / 20 °C

2: NaBH₄ / tetrahydrofuran / 8 h / Heating

3: 64 percent / conc. H₂SO₄, fuming HNO₃ / 1 h / 20 °C

4: H₂ / Raney Ni / methanol / 1 h / 20 °C

5: 46 percent / 6 h / 135 °C

6: 68 percent / PCl₅, POCl₃ / Heating

7: 65 percent / 25percent NH₄OH / 100 °C

With ammonium hydroxide; sodium tetrahydroborate; phosphorus pentachloride; sulfuric acid; hydrogen; nitric acid; trichlorophosphate; nickel; In tetrahydrofuran; methanol; ethanol;

Reference yield:

: 45715-13-7
2-(methylamino)-5-methylpyridine

: 155789-84-7
2-amino-3,6-dimethylimidazo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 64 percent / conc. H₂SO₄, fuming HNO₃ / 1 h / 20 °C

2: H₂ / Raney Ni / methanol / 1 h / 20 °C

3: 46 percent / 6 h / 135 °C

4: 68 percent / PCl₅, POCl₃ / Heating

5: 65 percent / 25percent NH₄OH / 100 °C

With ammonium hydroxide; phosphorus pentachloride; sulfuric acid; hydrogen; nitric acid; trichlorophosphate; nickel; In methanol;