2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline
CAS No.:552859-04-8
Molecular Formula:C₂₅H₃₁BrN₂O₂
Molecular Weight:471.437
Hs Code.:

Synonyms:2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline

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Chemical Property of 2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline

Chemical Property:

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Technology Process of 2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline

There total 1 articles about 2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 391954-24-8
4-(2-bromo-5-methoxybenzyl)piperidine hydrochloride

: 46185-24-4
1,2,3,4-tetrahydroquinoline-2-carboxylic acid

: 552859-04-8
2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃;

Reference yield:

: 552859-04-8
2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline

: 552859-05-9
2-((4-(2-bromo-5-isopropoxybenzyl)piperidin-1-yl)methyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: 2-((4-(2-Bromo-5-isopropoxybenzyl)piperidin-1-yl)carbonyl)-1,2,3,4-tetrahydroquinoline; With borane-THF; In tetrahydrofuran; at 20 ℃; for 3h;

With hydrogenchloride; In methanol; water; at 80 ℃; for 4h;

With sodium hydroxide; In water; pH=11;