Technology Process of 7-O-(tert-butyldiphenylsilyl)morpholinoinosine
There total 3 articles about 7-O-(tert-butyldiphenylsilyl)morpholinoinosine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
5'-O-(tert-butyldiphenylsilyl)inosine;
With
sodium periodate; ammonium biborate tetrahydrate;
In
methanol;
at 20 ℃;
for 1.5h;
Molecular sieve;
Inert atmosphere;
With
sodium cyanoborohydride; acetic acid;
In
methanol;
for 2h;
Molecular sieve;
Inert atmosphere;
DOI:10.1080/15257770.2012.724491
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / Molecular sieve; Inert atmosphere
2.1: sodium periodate; ammonium biborate tetrahydrate / methanol / 1.5 h / 20 °C / Molecular sieve; Inert atmosphere
2.2: 2 h / Molecular sieve; Inert atmosphere
With
1H-imidazole; sodium periodate; ammonium biborate tetrahydrate;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1080/15257770.2012.724491
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / Molecular sieve; Inert atmosphere
2.1: sodium periodate; ammonium biborate tetrahydrate / methanol / 1.5 h / 20 °C / Molecular sieve; Inert atmosphere
2.2: 2 h / Molecular sieve; Inert atmosphere
With
1H-imidazole; sodium periodate; ammonium biborate tetrahydrate;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1080/15257770.2012.724491
