Technology Process of C19H15N3S
There total 4 articles about C19H15N3S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium phosphate; copper(l) iodide; trans-1,2-Diaminocyclohexane;
In
1,4-dioxane;
for 13h;
Inert atmosphere;
Reflux;
DOI:10.1055/s-0033-1338951
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: CyJohnPhos; palladium diacetate / 1,4-dioxane / 0.17 h / Inert atmosphere
1.2: 1 h / Inert atmosphere; Reflux
2.1: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C
3.1: potassium phosphate; copper(l) iodide; trans-1,2-Diaminocyclohexane / 1,4-dioxane / 13 h / Inert atmosphere; Reflux
With
potassium phosphate; copper(l) iodide; trans-1,2-Diaminocyclohexane; palladium diacetate; trifluoroacetic acid; CyJohnPhos;
In
1,4-dioxane; dichloromethane;
1.1: |Suzuki Coupling / 1.2: |Suzuki Coupling;
DOI:10.1055/s-0033-1338951
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N-ethyl-N,N-diisopropylamine; dmap / dichloromethane / 0.5 h / 20 °C
2.1: CyJohnPhos; palladium diacetate / 1,4-dioxane / 0.17 h / Inert atmosphere
2.2: 1 h / Inert atmosphere; Reflux
3.1: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C
4.1: potassium phosphate; copper(l) iodide; trans-1,2-Diaminocyclohexane / 1,4-dioxane / 13 h / Inert atmosphere; Reflux
With
dmap; potassium phosphate; copper(l) iodide; trans-1,2-Diaminocyclohexane; palladium diacetate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; CyJohnPhos;
In
1,4-dioxane; dichloromethane;
2.1: |Suzuki Coupling / 2.2: |Suzuki Coupling;
DOI:10.1055/s-0033-1338951
