3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine
CAS No.:1262293-70-8
Molecular Formula:C₁₈H₁₃ClN₄O₄S₂
Molecular Weight:448.911
Hs Code.:

Synonyms:3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine

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Chemical Property of 3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine

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Technology Process of 3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine

There total 1 articles about 3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1262293-69-5
3-[6-chloro-2-(methylthio)pyrimidin-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

: 1262293-70-8
3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With Oxone; In water; ethyl acetate; at 80 ℃; for 16h;

Reference yield: 23.0%

: 1262293-70-8
3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine

: trans-cyclohexane-1,4-diamine

: trans-N-[4-chloro-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]cyclohexane-1,4-diamine

Guidance literature:: 3-(6-chloro-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenyl sulfonyl)-1H-pyrrolo[2,3-b]pyridine; trans-cyclohexane-1,4-diamine; With triethylamine; In 1,4-dioxane; at 60 ℃; for 2h;

With methanol; sodium hydroxide; at 20 ℃; for 1h;