C₃₆H₄₆N₂O₉

Base Information

• Chemical Name: C₃₆H₄₆N₂O₉
• CAS No.: 1438408-27-5
• Molecular Formula: C₃₆H₄₆N₂O₉
• Molecular Weight: 650.769
• Mol file: 1438408-27-5.mol

Synonyms:C₃₆H₄₆N₂O₉

Chemical Property of C₃₆H₄₆N₂O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₄₆N₂O₉

There total 8 articles about C₃₆H₄₆N₂O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

C36H46N2O9 (1438408-23-1) → C36H46N2O9 (1438408-27-5)

Guidance literature:

C₃₆H₄₆N₂O₉; With mercuric triflate; sodium hydrogencarbonate; In dichloromethane; at -20 ℃; for 10.5h; Inert atmosphere; Cooling with ice;

With lithium borohydride; triethyl borane; In tetrahydrofuran; dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere;

DOI:10.1039/c3cc42365d

Reference yield:

C14H25NO4 (1438408-16-2) → C36H46N2O9 (1438408-27-5)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 1H-imidazole; triphenylphosphine; iodine / dichloromethane / 2 h / Cooling with ice; Inert atmosphere

2.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / Cooling with ice; Inert atmosphere

2.2: 8 h / 20 °C / Inert atmosphere

2.3: 3.33 h / 20 °C / Inert atmosphere

3.1: C₁₅H₂₆Cl₂CuN₂O₂; triethylamine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

4.1: Dess-Martin periodane / dichloromethane / 5 h / Cooling with ice; Inert atmosphere

5.1: dichloromethane / 15 h / 50 °C / Inert atmosphere

6.1: sodium hydrogencarbonate; mercuric triflate / dichloromethane / 10.5 h / -20 °C / Inert atmosphere; Cooling with ice

6.2: 0.5 h / -78 °C / Inert atmosphere

With 1H-imidazole; C₁₅H₂₆Cl₂CuN₂O₂; iodine; mercuric triflate; sodium hydrogencarbonate; caesium carbonate; Dess-Martin periodane; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 4.1: |Dess-Martin Oxidation / 5.1: |Wittig Olefination;

DOI:10.1039/c3cc42365d

Reference yield:

C25H38N2O7 (1438408-19-5) → C36H46N2O9 (1438408-27-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: C₁₅H₂₆Cl₂CuN₂O₂; triethylamine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

2.1: Dess-Martin periodane / dichloromethane / 5 h / Cooling with ice; Inert atmosphere

3.1: dichloromethane / 15 h / 50 °C / Inert atmosphere

4.1: sodium hydrogencarbonate; mercuric triflate / dichloromethane / 10.5 h / -20 °C / Inert atmosphere; Cooling with ice

4.2: 0.5 h / -78 °C / Inert atmosphere

With C₁₅H₂₆Cl₂CuN₂O₂; mercuric triflate; sodium hydrogencarbonate; Dess-Martin periodane; triethylamine; In tetrahydrofuran; dichloromethane; 2.1: |Dess-Martin Oxidation / 3.1: |Wittig Olefination;

DOI:10.1039/c3cc42365d

upstream raw materials:

C₁₄H₂₅NO₄

C₁₄H₂₄INO₃

C₂₅H₃₈N₂O₇

C₃₆H₄₆N₂O₉

Downstream raw materials:

C₃₄H₄₄N₂O₈

C₃₄H₄₄N₂O₉

C₃₄H₄₅N₅O₉

C₂₆H₃₃N₅O₇*ClH