ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate

Base Information

• Chemical Name: ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate
• CAS No.: 1092961-64-2
• Molecular Formula: C₁₈H₂₂N₂O₄
• Molecular Weight: 330.384
• Mol file: 1092961-64-2.mol

Synonyms:ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate

Chemical Property of ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate

There total 1 articles about ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-methyl-but-2-ene (513-35-9) + ethyl 5-(allyloxy)-2-diazo-3-oxo-5-phenylpentanoate (1092961-60-8) → ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate (1092961-64-2)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; Reflux; Inert atmosphere;

DOI:10.1021/ol802334y

Reference yield:

ethyl 2-diazo-5-(3-methylbut-2-enyloxy)-3-oxo-5-phenylpentanoate (1092961-64-2) → ethyl 2-(2-methylbut-3-en-2-yl)-3-oxo-5-phenyltetrahydrofuran-2-carboxylate + ethyl 2-(2-methylbut-3-en-2-yl)-3-oxo-5-phenyltetrahydrofuran-2-carboxylate

Guidance literature:

With dirhodium tetraacetate; In dichloromethane; for 14h; optical yield given as %de; Reflux; Inert atmosphere;

DOI:10.1021/ol802334y

upstream raw materials:

2-methyl-but-2-ene

ethyl 5-(allyloxy)-2-diazo-3-oxo-5-phenylpentanoate