N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide

Base Information

• Chemical Name: N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide
• CAS No.: 1274906-14-7
• Molecular Formula: C₁₂H₁₀Cl₂N₂O₂S
• Molecular Weight: 317.196
• Mol file: 1274906-14-7.mol

Synonyms:N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide

Chemical Property of N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide

There total 1 articles about N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

CH3O3S(1-)*C5H5Cl2N2(1+) (1274906-37-4) + p-toluenesulfonyl chloride (98-59-9) → N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide (1274906-14-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 70 ℃; Cooling with ice;

DOI:10.1021/ol2002607

Reference yield: 90.0%

3-(2-cyclohexylethynyl)oxazolidin-2-one (1174523-94-4) + N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide (1274906-14-7) → (E)-N-(2-cyclohexylidene-1-(2-oxooxazolidin-3-yl)ethylidene)-4-methylbenzenesulfonamide (1274906-29-4)

Guidance literature:

With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]gold bis(trifluoromethanesulfonyl)imidate; In 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1021/ol2002607

Reference yield: 87.0%

N-(3,5-dichloro-1-pyridylidene)-4-methyl-benzenesulfonamide (1274906-14-7) + 1-(cyclohexylidenemethyl)-2-ethynylbenzene → 4-methyl-N-(1a'H-spiro[cyclohexane-1,1'-cyclopropa[a]inden]-6'(6a'H)-ylidene)benzenesulfonamide

Guidance literature:

With [1,3-bis(diisopropylphenyl)imidazol-2-ylidene]AuNTf₂; In 1,2-dichloro-ethane; at 80 ℃; for 2.5h; Inert atmosphere;

DOI:10.1002/adsc.201300090

upstream raw materials:

CH₃O₃S^(1-)*C₅H₅Cl₂N₂⁽¹⁺⁾

p-toluenesulfonyl chloride

Downstream raw materials:

(6E)-6-(2-oxooxazolidin-3-yl)-6-(tosylimino)hex-4-enyl acetate

(E)-N-(2-cyclohexylidene-1-(2-oxooxazolidin-3-yl)ethylidene)-4-methylbenzenesulfonamide

4-methyl-N-(1-(2-oxooxazolidin-3-yl)-5-phenylpent-2-enylidene)benzenesulfonamide

N-(6-(tert-butyldimethylsilyloxy)-1-(2-oxooxazolidin-3-yl)hex-2-enylidene)-4-methylbenzenesulfonamide