2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid

Base Information

Chemical Name:2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid
CAS No.:1622091-40-0
Molecular Formula:C₂₆H₂₈F₃N₇O₆
Molecular Weight:591.547
Hs Code.:

Synonyms:2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid

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Chemical Property of 2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid

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Technology Process of 2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid

There total 5 articles about 2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1622091-38-6
methyl 2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetate

: 1622091-40-0
2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid

Guidance literature:: With water; potassium carbonate; In acetone; at 20 ℃; for 16h;

Reference yield:

: 1622091-34-2
tert-butyl (3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)carbamate

: 1622091-40-0
2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / 4 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 4 h / 20 °C

3: potassium carbonate; water / acetone / 16 h / 20 °C

With water; potassium carbonate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; acetone;

Reference yield:

: 1287220-37-4
4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzoic acid

: 1622091-40-0
2-((3-(4-((4-((4-hydroxybenzyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)-2,2-dimethylpropyl)amino)-2-oxoacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / 1-methyl-pyrrolidin-2-one / 2 h / 20 °C

2: trifluoroacetic acid / dichloromethane / 4 h / 20 °C

3: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 4 h / 20 °C

4: potassium carbonate; water / acetone / 16 h / 20 °C

With water; potassium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane; acetone;