3-chloro-2,6-dimethyl-5-{4-[3-(4-{4-[(trifluoromethyl)oxy]phenyl}-1-piperidinyl)-1-propyn-1-yl]phenyl}-4(1H)-pyridinone trifluoroacetate

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Chemical Name:3-chloro-2,6-dimethyl-5-{4-[3-(4-{4-[(trifluoromethyl)oxy]phenyl}-1-piperidinyl)-1-propyn-1-yl]phenyl}-4(1H)-pyridinone trifluoroacetate
CAS No.:1235999-98-0
Molecular Formula:C₂HF₃O₂*C₂₈H₂₆ClF₃N₂O₂
Molecular Weight:628.999
Hs Code.:

Synonyms:3-chloro-2,6-dimethyl-5-{4-[3-(4-{4-[(trifluoromethyl)oxy]phenyl}-1-piperidinyl)-1-propyn-1-yl]phenyl}-4(1H)-pyridinone trifluoroacetate

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Chemical Property of 3-chloro-2,6-dimethyl-5-{4-[3-(4-{4-[(trifluoromethyl)oxy]phenyl}-1-piperidinyl)-1-propyn-1-yl]phenyl}-4(1H)-pyridinone trifluoroacetate

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Technology Process of 3-chloro-2,6-dimethyl-5-{4-[3-(4-{4-[(trifluoromethyl)oxy]phenyl}-1-piperidinyl)-1-propyn-1-yl]phenyl}-4(1H)-pyridinone trifluoroacetate

There total 1 articles about 3-chloro-2,6-dimethyl-5-{4-[3-(4-{4-[(trifluoromethyl)oxy]phenyl}-1-piperidinyl)-1-propyn-1-yl]phenyl}-4(1H)-pyridinone trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1235979-67-5
5-(4-bromophenyl)-3-chloro-2,6-dimethyl-4(1H)-pyridinone

: 1236000-61-5
1-(2-propyn-1-yl)-4-{4-[(trifluoromethyl)oxy]phenyl}piperidine

: 76-05-1
trifluoroacetic acid

: 1235999-98-0
3-chloro-2,6-dimethyl-5-{4-[3-(4-{4-[(trifluoromethyl)oxy]phenyl}-1-piperidinyl)-1-propyn-1-yl]phenyl}-4(1H)-pyridinone trifluoroacetate

Guidance literature:: 5-(4-bromophenyl)-3-chloro-2,6-dimethyl-4(1H)-pyridinone; 1-(2-propyn-1-yl)-4-{4-[(trifluoromethyl)oxy]phenyl}piperidine; With copper(l) iodide; triethylamine; tri tert-butylphosphoniumtetrafluoroborate; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 120 ℃; for 0.333333h; Microwave reactor; Microwave irradiation;

With hydrogenchloride; sodium hydroxide; In methanol; water;

trifluoroacetic acid; In water; acetonitrile;