2-(3,4-dimethoxy-phenyl)-5-[(4-hydroxy-benzyl)-methyl-amino]-2-isopropyl-pentanenitrile

Base Information

Chemical Name:2-(3,4-dimethoxy-phenyl)-5-[(4-hydroxy-benzyl)-methyl-amino]-2-isopropyl-pentanenitrile
CAS No.:1246457-14-6
Molecular Formula:C₂₄H₃₂N₂O₃
Molecular Weight:396.53
Hs Code.:

Synonyms:2-(3,4-dimethoxy-phenyl)-5-[(4-hydroxy-benzyl)-methyl-amino]-2-isopropyl-pentanenitrile

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Chemical Property of 2-(3,4-dimethoxy-phenyl)-5-[(4-hydroxy-benzyl)-methyl-amino]-2-isopropyl-pentanenitrile

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Technology Process of 2-(3,4-dimethoxy-phenyl)-5-[(4-hydroxy-benzyl)-methyl-amino]-2-isopropyl-pentanenitrile

There total 1 articles about 2-(3,4-dimethoxy-phenyl)-5-[(4-hydroxy-benzyl)-methyl-amino]-2-isopropyl-pentanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1246457-05-5
methanesulfonic acid 4-ethoxycarbonyloxy-benzyl ester

: 34245-14-2
2-(3,4-dimethoxyphenyl)-2-isopropyl-5-methylamino-pentanenitrile

: 1246457-14-6
2-(3,4-dimethoxy-phenyl)-5-[(4-hydroxy-benzyl)-methyl-amino]-2-isopropyl-pentanenitrile

Guidance literature:: methanesulfonic acid 4-ethoxycarbonyloxy-benzyl ester; 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-methylamino-pentanenitrile; With sodium hydrogencarbonate; potassium iodide; In methanol; for 72h; Inert atmosphere; Reflux;

With hydrogenchloride; In methanol; water; pH=1;

With ammonia; In methanol; water; pH=10;
DOI:10.1016/j.bmc.2010.07.031