2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine

Base Information

• Chemical Name: 2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine
• CAS No.: 62357-54-4
• Molecular Formula: C₁₂H₁₆Cl₃NO
• Molecular Weight: 296.624
• Mol file: 62357-54-4.mol

Synonyms:2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine

Chemical Property of 2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine

There total 1 articles about 2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(4R,6R)-carveol (99-48-9,1197-06-4,1197-07-5,2102-58-1,2102-59-2,5157-78-8,5503-11-7,7632-16-8,18383-51-2,22567-18-6,20307-86-2) + trichloroacetonitrile (545-06-2) → 2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine (62357-54-4)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1134/S1070428009060025

Reference yield: 60.0%

2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine (62357-54-4) → 2,2,2-trichloro-N-[(1S,5S)-5-isopropenyl-2-methylcyclohex-2-en-1-yl]acetamide (62357-55-5)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; for 7h; Reflux;

DOI:10.1134/S1070428009060025

Reference yield:

2,2,2-trichloro-1-[(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-yloxy]ethan-1-imine (62357-54-4) → (-)-N-cis-Carveylbenzamid

Guidance literature:

Multi-step reaction with 2 steps

1: xylene / Heating

2: (i) aq. NaOH, EtOH, (ii) /BRN= 471389/, Py, Et₂O

In xylene;

DOI:10.1246/bcsj.49.3247

upstream raw materials:

(4R,6R)-carveol

trichloroacetonitrile

Downstream raw materials:

2,2,2-trichloro-N-[(1S,5S)-5-isopropenyl-2-methylcyclohex-2-en-1-yl]acetamide