BETA-D-[1-13C]FRUCTOFURANOSYL ALPHA-D-GLUCOPYRANOSIDE

Base Information

• Chemical Name: BETA-D-[1-13C]FRUCTOFURANOSYL ALPHA-D-GLUCOPYRANOSIDE
• CAS No.: 154368-11-3
• Molecular Formula: C₁₂H₂₂O₁₁
• Molecular Weight: 343.289
• Mol file: 154368-11-3.mol

Synonyms:[1-13CFRU]SUCROSE;BETA-D-[1-13C]FRUCTOFURANOSYL ALPHA-D-GLUCOPYRANOSIDE

Chemical Property of BETA-D-[1-13C]FRUCTOFURANOSYL ALPHA-D-GLUCOPYRANOSIDE

Chemical Property:

• PSA: 189.53000
• LogP: -5.39560
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: Water (Slightly, Sonicated)

Purity/Quality:

97% ^*data from raw suppliers

Sucrose-1-13Cfru ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Labeled Sucrose (S697000). Yuanzhen sugar is a polysaccharide polymer, containing a certain amount of fructooligosaccharides.

Technology Process of BETA-D-[1-13C]FRUCTOFURANOSYL ALPHA-D-GLUCOPYRANOSIDE

There total 3 articles about BETA-D-[1-13C]FRUCTOFURANOSYL ALPHA-D-GLUCOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

uridine 5'-diphosphoglucose disodium salt (6858-46-4,7333-33-7,14656-80-5,28053-08-9,53829-41-7,108320-88-3,137868-52-1) + D-(1-13C)fructose → [1-13C1]-β-D-fructofuranosyl α-D-glucopyranoside (154368-11-3)

Guidance literature:

With potassium hydroxide; magnesium chloride; at 37 ℃; for 10h; sucrose synthetase (EC 2.4.1.13);

DOI:10.1016/0008-6215(93)84096-O

Reference yield:

UDP-glucose (133-89-1) + [1-13C1]-β-D-fructofuranose (117013-22-6) → [1-13C1]-β-D-fructofuranosyl α-D-glucopyranoside (154368-11-3)

Guidance literature:

With HEPES buffer; recombinant sucrose synthase 1 (EC 2.4.1.13, potato); alkaline phosphatase; In water; at 30 ℃; for 24h; pH=8.0; Enzymatic reaction;

DOI:10.1002/1615-4169(200108)343:6/7<655::AID-ADSC655>3.0.CO;2-A

Reference yield:

13C-C1-glucopyranose (40010-55-7,40010-56-8,56746-22-6,60821-16-1,60821-17-2,60821-20-7,60821-21-8) → [1-13C1]-β-D-fructofuranosyl α-D-glucopyranoside (154368-11-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 29 percent / phosphate buffer / 24 h / 37 °C / immobilized D-xylose (D-glucose) isomerase EC 5.3.1.5

2: 25 percent / aq. MgCl₂, KOH / 10 h / 37 °C / sucrose synthetase (EC 2.4.1.13)

With potassium hydroxide; phosphate buffer; magnesium chloride;

DOI:10.1016/0008-6215(93)84096-O

upstream raw materials:

uridine 5'-diphosphoglucose disodium salt

UDP-glucose

[1-¹³C₁]-β-D-fructofuranose

¹³C-C₁-glucopyranose

Refernces

• 1、 Roemer, Ulrike,Nettelstroth, Nadja,Koeckenberger, Walter,Elling, Lothar. "Characterization of Recombinant Sucrose Synthase 1 from Potato for the Synthesis of Sucrose Analogues". . p. 655 - 661. Retrieved 2007/10/03.