tetrakis[4-(1-(N₄-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane

Base Information

• Chemical Name: tetrakis[4-(1-(N₄-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane
• CAS No.: 1201839-76-0
• Molecular Formula: C₁₀₆H₉₆N₂₄O₁₆
• Molecular Weight: 1962.08

Synonyms:tetrakis[4-(1-(N₄-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane

Chemical Property of tetrakis[4-(1-(N₄-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane

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Technology Process of tetrakis[4-(1-(N₄-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane

There total 2 articles about tetrakis[4-(1-(N₄-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3'-azido-N4-benzoyl-2',3'-dideoxycytidine + 1,3,5,7-tetrakis(4-ethinylphenyl)adamantane (144970-32-1) → tetrakis[4-(1-(N4-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane (1201839-76-0)

Guidance literature:

With sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; copper(II) sulphate hydrate; In water; dimethyl sulfoxide; at 20 ℃; for 10h;

DOI:10.1039/b912189g

Reference yield: 79.0%

3'-azido-N4-benzoyl-2',3'-dideoxycytidine + 1,3,5,7-tetrakis(4-ethinylphenyl)adamantane (144970-32-1) → tetrakis[4-(1-(N4-benzoyl-2',3'-dideoxycytidine-3'-yl)-1,2,3-triazol-4-yl)phenyl]adamantane (1201839-76-0)

Guidance literature:

With copper(ll) sulfate pentahydrate; water; sodium L-ascorbate; In dimethyl sulfoxide; at 20 ℃; for 4h;

DOI:10.1002/anie.201006992

upstream raw materials:

1,3,5,7-tetrakis(4-ethinylphenyl)adamantane

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