C₄₀H₄₈O₇Si

Base Information

• Chemical Name: C₄₀H₄₈O₇Si
• CAS No.: 1193357-64-0
• Molecular Formula: C₄₀H₄₈O₇Si
• Molecular Weight: 668.902
• Mol file: 1193357-64-0.mol

Synonyms:C₄₀H₄₈O₇Si

Chemical Property of C₄₀H₄₈O₇Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₀H₄₈O₇Si

There total 15 articles about C₄₀H₄₈O₇Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C40H48BrIO7Si (1193357-63-9) → C40H48O7Si (1193357-64-0)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; phenyllithium; phenylmagnesium bromide; In tetrahydrofuran; diethyl ether; hexane; at -78 - 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1246/cl.2009.934

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C40H48O7Si (1193357-64-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: dmap / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: tributylphosphine; diamide / toluene / 2.5 h / 0 - 20 °C / Inert atmosphere

4.1: dilithium tetrabromonickelate(II) / tetrahydrofuran; toluene / 18.5 h / 0 °C / Inert atmosphere

5.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 °C / Inert atmosphere

6.1: N,N,N,N,N,N-hexamethylphosphoric triamide; phenyllithium; phenylmagnesium bromide / tetrahydrofuran; diethyl ether; hexane / 0.5 h / -78 - 0 °C / Inert atmosphere

With 1H-imidazole; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; tributylphosphine; dilithium tetrabromonickelate(II); diamide; tetrabutyl ammonium fluoride; phenyllithium; phenylmagnesium bromide; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; 3.1: |Mitsunobu Displacement;

DOI:10.1246/cl.2009.934

Reference yield:

C31H40O6S (1309060-44-3) → C40H48O7Si (1193357-64-0)

Guidance literature:

Multi-step reaction with 9 steps

1.1: potassium carbonate / methanol / 3 h / 0 °C / Inert atmosphere

2.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 - 20 °C / Inert atmosphere

3.1: 10 wt% Pd(OH)2 on carbon; hydrogen / ethyl acetate / 6.5 h / 20 °C

4.1: dmap / dichloromethane / 1 h / 20 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

5.2: Inert atmosphere

6.1: tributylphosphine; diamide / toluene / 2.5 h / 0 - 20 °C / Inert atmosphere

7.1: dilithium tetrabromonickelate(II) / tetrahydrofuran; toluene / 18.5 h / 0 °C / Inert atmosphere

8.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 °C / Inert atmosphere

9.1: N,N,N,N,N,N-hexamethylphosphoric triamide; phenyllithium; phenylmagnesium bromide / tetrahydrofuran; diethyl ether; hexane / 0.5 h / -78 - 0 °C / Inert atmosphere

With 1H-imidazole; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; tributylphosphine; dilithium tetrabromonickelate(II); diamide; 10 wt% Pd(OH)2 on carbon; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; phenyllithium; phenylmagnesium bromide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene; 6.1: |Mitsunobu Displacement;

DOI:10.1246/cl.2009.934

upstream raw materials:

C₁₄H₁₈O₅

C₃₄H₃₃IO₇

C₃₄H₃₄BrIO₇

C₄₀H₄₈BrIO₇Si

Downstream raw materials:

C₃₅H₄₀O₅Si

C₂₉H₂₆O₅