1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

Base Information

Chemical Name:1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea
CAS No.:1449694-06-7
Molecular Formula:C₁₉H₂₂N₄O₄
Molecular Weight:370.408
Hs Code.:

Synonyms:1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

Suppliers and Price of 1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

There total 3 articles about 1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1092096-40-6
C₁₀H₁₃N₃O₂

: 56651-60-6
4-methoxybenzyl isocyanate

: 1449694-06-7
1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 1.33333h;
DOI:10.1039/c3md00094j

Reference yield:

: deaminomethyl debromoagelastatin

: 1449694-06-7
1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: dimethyl sulfoxide; water / 16 h / 130 °C / Sealed tube

2: N,N-dimethyl-formamide / 1.33 h / 20 °C

In water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1039/c3md00094j

Reference yield:

: 1092096-33-7
(1R,9S,10S,14R)-13-oxa-2,8,11-triazatetracyclo[7.6.0.0^2,6.0^10,14]pentadeca-3,5-diene-7,12-dione

: 1449694-06-7
1-((2R,3S,3aS,9aR)-2-hydroxy-5-oxo-2,3,3a,4,5,9a-hexahydro-1H-cyclopenta[e]pyrrolo[1,2-a]pyrazin-3-yl)-3-(4-methoxybenzyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: dimethyl sulfoxide; water / 16 h / 130 °C

2: N,N-dimethyl-formamide / 1.33 h / 20 °C

In water; dimethyl sulfoxide; N,N-dimethyl-formamide;