tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate

Base Information

Chemical Name:tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate
CAS No.:1070668-47-1
Molecular Formula:C₃₀H₃₅FN₂O₂
Molecular Weight:474.619
Hs Code.:

Synonyms:tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate

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Chemical Property of tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate

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Technology Process of tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate

There total 1 articles about tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1070668-45-9
3-benzyl-6-fluoro-1,2,3,4-tetrahydroisoquinoline

: 136159-63-2
N-(t-butyloxycarbonyl)-N-benzylaminoacetaldehyde

: 1070668-47-1
tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate

Guidance literature:: 3-benzyl-6-fluoro-1,2,3,4-tetrahydroisoquinoline; N-(t-butyloxycarbonyl)-N-benzylaminoacetaldehyde; With sodium tris(acetoxy)borohydride; acetic acid; In toluene; at 20 ℃; for 0.5h;

With water; In toluene;

Reference yield: 99.0%

: 1070668-47-1
tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate

: 1070663-61-4
N-benzyl-2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethanamine

Guidance literature:: tert-butyl benzyl[2-[3-benzyl-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl]ethyl]carbamate; With hydrogenchloride; water; In ethyl acetate; at 20 ℃; for 0.5h;

With sodium hydrogencarbonate; In water; ethyl acetate;