3-Furancarboxylicacid,4-methyl-,ethylester(9CI)

Base Information

• Chemical Name: 3-Furancarboxylicacid,4-methyl-,ethylester(9CI)
• CAS No.: 154222-96-5
• Molecular Formula: C8H10 O3
• Molecular Weight: 154.166
• Mol file: 154222-96-5.mol

Synonyms:3-Furancarboxylicacid,4-methyl-,ethylester(9CI)

Chemical Property of 3-Furancarboxylicacid,4-methyl-,ethylester(9CI)

Chemical Property:

• PSA: 39.44000
• LogP: 1.76470

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Furancarboxylicacid,4-methyl-,ethylester(9CI)

There total 2 articles about 3-Furancarboxylicacid,4-methyl-,ethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(2S,3R)-2-bromo-3-propargyloxy-3-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyloxy)propanoate → 2,3,4,5-tetra-O-acetyl-D-glucopyranose (3947-62-4,6207-76-7,19235-21-3,22554-70-7,22860-22-6,47339-09-3,57884-82-9,62057-79-8,70191-05-8,109525-54-4,140147-37-1,10343-06-3) + (2R*,3S*)-3-ethoxycarbonyl-4-methylene-2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)tetrahydrofuran + ethyl 4-methylfuran-3-carboxylate (154222-96-5)

Guidance literature:

With 1,1,1,3',3',3'-hexafluoro-propanol; tetrabutylammomium bromide; In propan-1-ol; at 20 ℃; diastereospecific reaction; Electrolysis; Green chemistry;

DOI:10.1149/2.1031414jes

Reference yield: 60.0%

(2S,3R)-2-bromo-3-propargyloxy-3-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyloxy)propanoate → 2,3,4,5-tetra-O-acetyl-D-glucopyranose (3947-62-4,6207-76-7,19235-21-3,22554-70-7,22860-22-6,47339-09-3,57884-82-9,62057-79-8,70191-05-8,109525-54-4,140147-37-1,10343-06-3) + ethyl 4-methylfuran-3-carboxylate (154222-96-5)

Guidance literature:

With 1,1,1,3',3',3'-hexafluoro-propanol; [Ni(1,4,8,11-tetramethyl-1,4,8,11-tetraazacyclotetradecane)]Br₂; tetrabutylammomium bromide; In ethanol; Reagent/catalyst; Electrolysis; Green chemistry;

DOI:10.1149/2.1031414jes

Reference yield:

ethyl 4-methylfuran-3-carboxylate (154222-96-5) → ((4-(ethoxycarbonyl)-3-methylfuran-2-yl)methyl)triphenylphosphonium chloride

Guidance literature:

Multi-step reaction with 2 steps

1: zinc(II) chloride; hydrogenchloride / diethyl ether; chloroform / 3 h / 60 - 65 °C / Inert atmosphere

2: toluene / 12 h / 20 °C / Reflux

With hydrogenchloride; zinc(II) chloride; In diethyl ether; chloroform; toluene;

DOI:10.1016/j.ejmech.2016.02.074

Refernces