Technology Process of octadecahydro-7-benzyl-1,6-methanocyclopenta<3,4>pentaleno<2,1,6-cde>pentaleno<2,1,6-gha>pentalene-7-carboxaldehyde
There total 5 articles about octadecahydro-7-benzyl-1,6-methanocyclopenta<3,4>pentaleno<2,1,6-cde>pentaleno<2,1,6-gha>pentalene-7-carboxaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3 A molecular sieve; sodium acetate; pyridinium chlorochromate;
In
dichloromethane;
for 0.666667h;
Ambient temperature;
DOI:10.1021/jo00383a017
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) Li, NH3 / 1.) 1,2-dimethoxyethane, -78 deg C, 30 min, 2.) 1,2-dimethoxyethane, a) -78 deg C, 30 min, b) -33 deg C, 30 min
2: 2.) p-toluenosulfonic acid / 1.) tert-butyl alcohol, benzene, irradiation, 23 h, 2.) benzene, reflux, 5 h
3: 95.1 percent / H2NNH2, 30percent aq. H2O2 / tetrahydrofuran; ethanol / Ambient temperature
4: 96.7 percent / diisobutyl aluminium hydride / benzene / 24 h
5: 86 percent / sodium acetate, 3-A molecular sieves, pyridinium chlorochromate / CH2Cl2 / 0.67 h / Ambient temperature
With
3 A molecular sieve; ammonia; dihydrogen peroxide; sodium acetate; lithium; diisobutylaluminium hydride; toluene-4-sulfonic acid; pyridinium chlorochromate; hydrazine;
In
tetrahydrofuran; ethanol; dichloromethane; benzene;
DOI:10.1021/jo00383a017
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96.7 percent / diisobutyl aluminium hydride / benzene / 24 h
2: 86 percent / sodium acetate, 3-A molecular sieves, pyridinium chlorochromate / CH2Cl2 / 0.67 h / Ambient temperature
With
3 A molecular sieve; sodium acetate; diisobutylaluminium hydride; pyridinium chlorochromate;
In
dichloromethane; benzene;
DOI:10.1021/jo00383a017
