Technology Process of (2R,3R)-3,6-Bis-benzyloxy-2-methyl-hexanal
There total 6 articles about (2R,3R)-3,6-Bis-benzyloxy-2-methyl-hexanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: NaH; tetrabutylammonium iodide / dimethylformamide; various solvent(s) / 0.5 h / 0 °C
1.2: dimethylformamide; various solvent(s) / 0 - 20 °C
2.1: OsO4; 4-methylmorpholine N-oxide / acetone; H2O; toluene / 20 °C
3.1: 3.2 g / lead(IV) acetate / benzene / 2 h / 20 °C
With
lead(IV) acetate; osmium(VIII) oxide; tetra-(n-butyl)ammonium iodide; sodium hydride; 4-methylmorpholine N-oxide;
In
water; N,N-dimethyl-formamide; acetone; toluene; benzene;
DOI:10.1021/ol990379y
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 93 percent / oxalyl chloride; dimethyl sulfoxide; Et3N / CH2Cl2 / -78 - 20 °C
2.1: NaH / tetrahydrofuran / 0 - 20 °C
2.2: 96 percent / tetrabutylammonium iodide / tetrahydrofuran / 12 h / 20 °C
3.1: OsO4; NMO / tetrahydrofuran; H2O / 12 h / 20 °C
4.1: NaIO4; aq. buffer / tetrahydrofuran / 2 h / 0 °C / pH 7
With
sodium periodate; osmium(VIII) oxide; N-methyl-2-indolinone; oxalyl dichloride; sodium hydride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; dichloromethane; water;
1.1: Swern oxidation;
DOI:10.1021/ja057686l
- Guidance literature:
-
With
sodium periodate;
In
tetrahydrofuran;
at 0 ℃;
for 2h;
pH=7;
DOI:10.1021/ja057686l
