16,16-Dimethylprostagladin A2

Base Information

Chemical Name:16,16-Dimethylprostagladin A2
CAS No.:41691-92-3
Molecular Formula:C₂₂H₃₄O₄
Molecular Weight:362.51
Hs Code.:
UNII:C181YIS8NP
Wikidata:Q27275050
Metabolomics Workbench ID:2445
Mol file:41691-92-3.mol

Synonyms:41691-92-3;16,16-dimethyl-PGA2;16,16-Dimethylprostagladin A2;16,16-dimethyl Prostaglandin A2;C181YIS8NP;UNII-C181YIS8NP;(Z)-7-[(1R,2S)-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid;16,16-dimethyl-Prostaglandin A2;(5Z,13E,15R)-15-Hydroxy-16,16-dimethyl-9-oxoprosta-5,10,13-trien-1-oic acid;Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)-;9oxo-15R-hydroxy-16,16-dimethyl-5Z,10Z,13E-prostatrienoic acid;LMFA03010086;SCHEMBL5700545;CHEBI:178528;HMS3648K07;AKOS040755004;PD021384;SR-01000946230;SR-01000946230-1;Q27275050

Suppliers and Price of 16,16-Dimethylprostagladin A2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
16,16-Dimethyl Prostaglandin A2
1mg
$ 333.00

TRC
16,16-DimethylProstaglandinA2
2.5mg
$ 130.00

Cayman Chemical
16,16-dimethyl Prostaglandin A2 ≥98%
5mg
$ 333.00

Cayman Chemical
16,16-dimethyl Prostaglandin A2 ≥98%
1mg
$ 74.00

Cayman Chemical
16,16-dimethyl Prostaglandin A2 ≥98%
10mg
$ 592.00

AK Scientific
16,16-DimethylprostaglandinA2
5mg
$ 549.00

AHH
16,16-DimethylprostaglandinA2 98%
0.01g
$ 388.00

Total 2 raw suppliers

Chemical Property of 16,16-Dimethylprostagladin A2

Chemical Property:

Boiling Point:526.9±50.0 °C(Predicted)
PKA:4.75±0.10(Predicted)
PSA：74.60000
Density:1.078±0.06 g/cm3(Predicted)
LogP:4.69240
XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:12
Exact Mass:362.24570956
Heavy Atom Count:26
Complexity:542

Purity/Quality:

≥98% ^*data from raw suppliers

16,16-Dimethyl Prostaglandin A2 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC(C)(C)C(C=CC1C=CC(=O)C1CC=CCCCC(=O)O)O
Isomeric SMILES:CCCCC(C)(C)[C@@H](/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O
Description 16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 μg/ml. Daily infusion of 10 μg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.
Uses 16,16-dimethyl Prostaglandin A2 is a PGA2 analog studied for its antiproliferative properties.

Technology Process of 16,16-Dimethylprostagladin A2

There total 1 articles about 16,16-Dimethylprostagladin A2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: