methyl 3-α-(tert-butyloxycarbonyl)-N^ε-(benzyloxycarbonyl)lisinylalaninyl-N^ε-(benzyloxycarbonyl)lysinyl>propionate

Base Information

• Chemical Name: methyl 3-α-(tert-butyloxycarbonyl)-N^ε-(benzyloxycarbonyl)lisinylalaninyl-N^ε-(benzyloxycarbonyl)lysinyl>propionate
• CAS No.: 94859-83-3
• Molecular Formula: C₄₀H₅₇N₅O₁₁
• Molecular Weight: 783.919

Synonyms:methyl 3-α-(tert-butyloxycarbonyl)-N^ε-(benzyloxycarbonyl)lisinylalaninyl-N^ε-(benzyloxycarbonyl)lysinyl>propionate

Chemical Property of methyl 3-α-(tert-butyloxycarbonyl)-N^ε-(benzyloxycarbonyl)lisinylalaninyl-N^ε-(benzyloxycarbonyl)lysinyl>propionate

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

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Technology Process of methyl 3-α-(tert-butyloxycarbonyl)-N^ε-(benzyloxycarbonyl)lisinylalaninyl-N^ε-(benzyloxycarbonyl)lysinyl>propionate

There total 1 articles about methyl 3-α-(tert-butyloxycarbonyl)-N^ε-(benzyloxycarbonyl)lisinylalaninyl-N^ε-(benzyloxycarbonyl)lysinyl>propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3,3'-Dimethoxycarbonylpropanoic anhydride (52944-79-3) + Boc-Lys(Z)-Ala-Lys(Z)-OH (94904-24-2) → methyl 3-α-(tert-butyloxycarbonyl)-Nε-(benzyloxycarbonyl)lisinylalaninyl-Nε-(benzyloxycarbonyl)lysinyl>propionate (94859-83-3)

Guidance literature:

With pyridine; dmap; triethylamine; at 45 - 50 ℃; for 1h;

DOI:10.1021/jo00207a038

upstream raw materials:

3,3'-Dimethoxycarbonylpropanoic anhydride

Boc-Lys(Z)-Ala-Lys(Z)-OH

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