Technology Process of (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate
There total 7 articles about (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: benzene / 6 h / Heating
2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 10 min, 2.) hexane, THF, 0 deg C, 3 h
3: 83 percent / 1 M aq. NaOH / methanol / 96 h / Ambient temperature
4: 100 percent / CH2Cl2 / 0.5 h / Ambient temperature
With
sodium hydroxide; n-butyllithium;
In
methanol; dichloromethane; benzene;
DOI:10.1039/c39910000351
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 63 percent / pyridine*SO3, Et3N / dimethylformamide / 0.5 h / Ambient temperature
2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 10 min, 2.) hexane, THF, 0 deg C, 3 h
3: 83 percent / 1 M aq. NaOH / methanol / 96 h / Ambient temperature
4: 100 percent / CH2Cl2 / 0.5 h / Ambient temperature
With
sodium hydroxide; n-butyllithium; sulfur trioxide pyridine complex; triethylamine;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c39910000351
