(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

Base Information

Chemical Name:(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate
CAS No.:134526-68-4
Molecular Formula:C₂HF₃O₂*C₂₀H₂₉NO₃
Molecular Weight:445.479
Hs Code.:

Synonyms:(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

Suppliers and Price of (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

There total 7 articles about (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 134440-92-9
(2S,3S,4E,6E,8S,9S)-3-(tert-butoxycarbonyl)amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoic acid

: 76-05-1
trifluoroacetic acid

: 134526-68-4
(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

Guidance literature:: In dichloromethane; for 0.5h; Ambient temperature;
DOI:10.1039/c39910000351

Reference yield:

: 126399-11-9,143571-39-5
cis/trans-(4S,5S)-1-bromo-5-methoxy-2,4-dimethyl-6-phenylhex-2-ene

: 134526-68-4
(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: benzene / 6 h / Heating

2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 10 min, 2.) hexane, THF, 0 deg C, 3 h

3: 83 percent / 1 M aq. NaOH / methanol / 96 h / Ambient temperature

4: 100 percent / CH₂Cl₂ / 0.5 h / Ambient temperature

With sodium hydroxide; n-butyllithium; In methanol; dichloromethane; benzene;
DOI:10.1039/c39910000351

Reference yield:

: 134440-96-3
(2S,3R)-N-tert-butoxycarbonyl-2-methyl-3-amino-4-hydroxy methyl butanoate

: 134526-68-4
(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: 63 percent / pyridine*SO₃, Et₃N / dimethylformamide / 0.5 h / Ambient temperature

2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 10 min, 2.) hexane, THF, 0 deg C, 3 h

3: 83 percent / 1 M aq. NaOH / methanol / 96 h / Ambient temperature

4: 100 percent / CH₂Cl₂ / 0.5 h / Ambient temperature

With sodium hydroxide; n-butyllithium; sulfur trioxide pyridine complex; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c39910000351