methyl N-(tert-butoxycarbonyl)-3,3,3-trifluoro-2-[3-(4-fluorophenyl)isoxazol-5-yl]alaninate

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Chemical Name:methyl N-(tert-butoxycarbonyl)-3,3,3-trifluoro-2-[3-(4-fluorophenyl)isoxazol-5-yl]alaninate
CAS No.:1345465-57-7
Molecular Formula:C₁₈H₁₈F₄N₂O₅
Molecular Weight:418.345
Hs Code.:

Synonyms:methyl N-(tert-butoxycarbonyl)-3,3,3-trifluoro-2-[3-(4-fluorophenyl)isoxazol-5-yl]alaninate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl N-(tert-butoxycarbonyl)-3,3,3-trifluoro-2-[3-(4-fluorophenyl)isoxazol-5-yl]alaninate

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Technology Process of methyl N-(tert-butoxycarbonyl)-3,3,3-trifluoro-2-[3-(4-fluorophenyl)isoxazol-5-yl]alaninate

There total 1 articles about methyl N-(tert-butoxycarbonyl)-3,3,3-trifluoro-2-[3-(4-fluorophenyl)isoxazol-5-yl]alaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1035805-03-8
methyl 2-[(tert-butoxycarbonyl)amino]-2-(trifluoromethyl)but-3-ynoate

: 42202-95-9
4-fluoro-N-hydroxybenzimidoyl chloride

: 1345465-57-7
methyl N-(tert-butoxycarbonyl)-3,3,3-trifluoro-2-[3-(4-fluorophenyl)isoxazol-5-yl]alaninate

Guidance literature:: With copper(ll) sulfate pentahydrate; potassium hydrogencarbonate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; regioselective reaction;
DOI:10.1039/c1ob06040f