N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide

Base Information

• Chemical Name: N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide
• CAS No.: 306775-11-1
• Molecular Formula: C₁₉H₂₆BNO₄S
• Molecular Weight: 375.297
• Mol file: 306775-11-1.mol

Synonyms:N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide

Chemical Property of N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide

There total 3 articles about N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N-tosyl-N-allylpropargylamine (133886-40-5) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide (306775-11-1)

Guidance literature:

With C₄₀H₅₀IrNP₂; at 60 ℃; for 5h;

DOI:10.1039/c5sc02161h

Reference yield:

2-ethoxy-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (1126-93-8) + N-tosyl-N-allylpropargylamine (133886-40-5) → N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide (306775-11-1)

Guidance literature:

N-tosyl-N-allylpropargylamine; With lithium diisopropyl amide; In diethyl ether; at -78 ℃;

2-ethoxy-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; In diethyl ether;

With hydrogenchloride; In diethyl ether; at -78 - 20 ℃;

DOI:10.1002/1521-3773(20000901)39:17<3101::AID-ANIE3101>3.0.CO;2-I

Reference yield:

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (61676-62-8) + N-tosyl-N-allylpropargylamine (133886-40-5) → N-allyl-N-(3-pinacolborylprop-2-yn-1-yl) toluenesulfonamide (306775-11-1)

Guidance literature:

N-tosyl-N-allylpropargylamine; With lithium diisopropyl amide; In diethyl ether; at -78 ℃;

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In diethyl ether;

With hydrogenchloride; In diethyl ether; at -78 - 20 ℃;

DOI:10.1002/1521-3773(20000901)39:17<3101::AID-ANIE3101>3.0.CO;2-I

upstream raw materials:

2-ethoxy-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

N-tosyl-N-allylpropargylamine

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

Downstream raw materials:

3-[1-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-vinyl]-1-(toluene-4-sulfonyl)-2,5-dihydro-1H-pyrrole