(+/-)-N-{3-[4-amino-2-oxo-1-(tetrahydro-2-thienyl)-1,2-dihydropyrimidin-5-yl]prop-2-yn-1-yl}cyclohexanesulfonamide

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Chemical Name:(+/-)-N-{3-[4-amino-2-oxo-1-(tetrahydro-2-thienyl)-1,2-dihydropyrimidin-5-yl]prop-2-yn-1-yl}cyclohexanesulfonamide
CAS No.:1055311-76-6
Molecular Formula:C₁₇H₂₄N₄O₃S₂
Molecular Weight:396.535
Hs Code.:

Synonyms:(+/-)-N-{3-[4-amino-2-oxo-1-(tetrahydro-2-thienyl)-1,2-dihydropyrimidin-5-yl]prop-2-yn-1-yl}cyclohexanesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+/-)-N-{3-[4-amino-2-oxo-1-(tetrahydro-2-thienyl)-1,2-dihydropyrimidin-5-yl]prop-2-yn-1-yl}cyclohexanesulfonamide

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Technology Process of (+/-)-N-{3-[4-amino-2-oxo-1-(tetrahydro-2-thienyl)-1,2-dihydropyrimidin-5-yl]prop-2-yn-1-yl}cyclohexanesulfonamide

There total 1 articles about (+/-)-N-{3-[4-amino-2-oxo-1-(tetrahydro-2-thienyl)-1,2-dihydropyrimidin-5-yl]prop-2-yn-1-yl}cyclohexanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1055311-95-9
N-prop-2-yn-1-ylcyclohexanesulfonamide

: 945980-58-5
(±)-5-iodo-1-(tetrahydrothien-2-yl)cytosine

: 1055311-76-6
(+/-)-N-{3-[4-amino-2-oxo-1-(tetrahydro-2-thienyl)-1,2-dihydropyrimidin-5-yl]prop-2-yn-1-yl}cyclohexanesulfonamide

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 25 ℃; for 3h; Inert atmosphere; Darkness;
DOI:10.1039/b804375b