potassium ortho-fluorobenzoate

Base Information

• Chemical Name: potassium ortho-fluorobenzoate
• CAS No.: 16463-37-9
• Molecular Formula: C₇H₄FO₂*K
• Molecular Weight: 178.204
• Mol file: 16463-37-9.mol

Synonyms:potassium ortho-fluorobenzoate

Chemical Property of potassium ortho-fluorobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of potassium ortho-fluorobenzoate

There total 1 articles about potassium ortho-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

o-fluoro-benzoic acid (445-29-4) → potassium ortho-fluorobenzoate (16463-37-9)

Guidance literature:

With potassium tert-butylate; In ethanol; at 20 ℃; for 1.5h;

DOI:10.1002/anie.200904916

Reference yield: 99.0%

naphthalen-2-yl tosylate (7385-85-5) + potassium ortho-fluorobenzoate (16463-37-9) → 2-(2-fluorophenyl)naphthalene (22082-95-7)

Guidance literature:

With copper(I) oxide; palladium(II) acetylacetonate; 1,10-Phenanthroline; XPhos; In 1-methyl-pyrrolidin-2-one; at 50 - 180 ℃; for 0.116667h; Inert atmosphere; Microwave irradiation;

DOI:10.1002/anie.200905953

Reference yield: 91.0%

(4-bromophenyl)(phenyl)methanone (90-90-4) + potassium ortho-fluorobenzoate (16463-37-9) → 4-(2-fluorophenyl)benzophenone (1448355-83-6)

Guidance literature:

With palladium(II) acetylacetonate; N,N,N,N,-tetramethylethylenediamine; copper(I) bromide; In 1-methyl-pyrrolidin-2-one; at 170 ℃; for 16h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/adsc.201201018

upstream raw materials:

o-fluoro-benzoic acid

Downstream raw materials:

ortho-diphenylphosphinobenzoic acid

2-(2-fluorophenyl)naphthalene

4-(2-fluorophenyl)benzophenone

3-(2-fluorophenyl)-1,2-dihydronaphthalene

Refernces

• 1、 Bhadra, Sukalyan,Dzik, Wojciech I.,Goossen, Lukas J.. "Decarboxylative etherification of aromatic carboxylic acids". supporting information; experimental part. p. 9938 - 9941. Retrieved 2012/08/08.
• 2、 Goossen, Luksa J.,Rodriguez, Nuria,Lange, Paul P.,Linder, Christophe. "Decarboxylative cross-coupling of aryl tosylates with aromatic carboxylate salts". supporting information; experimental part. p. 1111 - 1114. Retrieved 2010/04/29.