Technology Process of C17H18ClN5O
There total 5 articles about C17H18ClN5O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 1 h / Reflux
2: N-ethyl-N,N-diisopropylamine / butan-1-ol; isopropyl alcohol / Reflux
3: tetrabutyl-ammonium chloride; ammonium formate / palladium 10% on activated carbon / water; tetrahydrofuran; methanol / 2.5 h / 60 °C
4: hydrogenchloride / methanol / 20 °C
With
hydrogenchloride; tetrabutyl-ammonium chloride; ammonium formate; N-ethyl-N,N-diisopropylamine; trichlorophosphate;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; water; isopropyl alcohol; butan-1-ol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: N-ethyl-N,N-diisopropylamine / butan-1-ol; isopropyl alcohol / Reflux
2: tetrabutyl-ammonium chloride; ammonium formate / palladium 10% on activated carbon / water; tetrahydrofuran; methanol / 2.5 h / 60 °C
3: hydrogenchloride / methanol / 20 °C
With
hydrogenchloride; tetrabutyl-ammonium chloride; ammonium formate; N-ethyl-N,N-diisopropylamine;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; water; isopropyl alcohol; butan-1-ol;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium methylate / methanol / 2 h / 55 °C
1.2: 0.5 h
2.1: hydrogenchloride; sodium nitrite / water
2.2: 0.5 h
3.1: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 1 h / Reflux
4.1: N-ethyl-N,N-diisopropylamine / butan-1-ol; isopropyl alcohol / Reflux
5.1: tetrabutyl-ammonium chloride; ammonium formate / palladium 10% on activated carbon / water; tetrahydrofuran; methanol / 2.5 h / 60 °C
6.1: hydrogenchloride / methanol / 20 °C
With
hydrogenchloride; tetrabutyl-ammonium chloride; ammonium formate; sodium methylate; N-ethyl-N,N-diisopropylamine; sodium nitrite; trichlorophosphate;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; water; isopropyl alcohol; butan-1-ol;