2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate

Base Information

• Chemical Name: 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate
• CAS No.: 155195-29-2
• Molecular Formula: C₃₄H₄₆Cl₃NO₉Si₂
• Molecular Weight: 775.271
• Mol file: 155195-29-2.mol

Synonyms:2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate

Chemical Property of 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate

There total 2 articles about 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

trichloroacetonitrile (545-06-2) + 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranose (155195-28-1) → 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate (155195-29-2)

Guidance literature:

With potassium carbonate; In dichloromethane; for 4h; Ambient temperature;

Reference yield:

Benzyl 2,3-di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-α-D-mannopyranoside (145259-94-5) → 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate (155195-29-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / H₂ / 10percent Pd/C / ethyl acetate / 18 h

2: 89 percent / K₂CO₃ / CH₂Cl₂ / 4 h / Ambient temperature

With hydrogen; potassium carbonate; palladium on activated charcoal; In dichloromethane; ethyl acetate;

Reference yield: 89.0%

octanol (111-87-5) + 2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranosyl trichloroacetimidate (155195-29-2) → octyl 2,3-di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside (187140-00-7)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -30 ℃; for 0.5h;

DOI:10.1016/S0008-6215(96)00215-7

upstream raw materials:

trichloroacetonitrile

2,3-Di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranose

Benzyl 2,3-di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-α-D-mannopyranoside

Downstream raw materials:

octyl 2,3-di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside

octyl 2,3-di-O-benzoyl-4-O-(1-fluoro-1,1,3,3-tetraisopropyl-1,3-disiloxane-3-yl)-α-D-mannopyranoside

octyl (2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3-di-O-benzoyl-α-D-mannopyranoside