C₆₅H₈₂I₂O₁₄Si₂

Base Information

• Chemical Name: C₆₅H₈₂I₂O₁₄Si₂
• CAS No.: 121328-72-1
• Molecular Formula: C₆₅H₈₂I₂O₁₄Si₂
• Molecular Weight: 1397.34
• Mol file: 121328-72-1.mol

Synonyms:C₆₅H₈₂I₂O₁₄Si₂

Chemical Property of C₆₅H₈₂I₂O₁₄Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₆₅H₈₂I₂O₁₄Si₂

There total 7 articles about C₆₅H₈₂I₂O₁₄Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

1,5-anhydro-3,6-di-O-benzoyl-2-deoxy-D-arabino-hex-1-enitol (58871-06-0) + (2R,3S,4R)-4-((2S,3S,4S,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-3-iodo-tetrahydro-pyran-2-yloxy)-3-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,4-dihydro-2H-pyran (121328-70-9) → C65H82I2O14Si2 (121328-72-1)

Guidance literature:

With iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/ja00199a027

Reference yield:

3,4,6-tri-O-benzyl-D-glucal (55628-54-1) → C65H82I2O14Si2 (121328-72-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 76 percent / 4A molecular sieves, I(sym-collidine)2ClO₄ / CH₂Cl₂ / 2 h / Ambient temperature

2: 99 percent / NaOH / methanol; diethyl ether / 1 h / Ambient temperature

3: 79 percent / imidazole / dimethylformamide / 15 h

4: 64 percent / 4A molecular sieves, I(sym-collidine)2ClO₄ / CH₂Cl₂ / 2 h / Ambient temperature

With 1H-imidazole; sodium hydroxide; iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; In methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja00199a027

Reference yield:

6-O-Benzoyl-D-glucal (58871-05-9) → C65H82I2O14Si2 (121328-72-1)

Guidance literature:

Multi-step reaction with 5 steps

2: 76 percent / 4A molecular sieves, I(sym-collidine)2ClO₄ / CH₂Cl₂ / 2 h / Ambient temperature

3: 99 percent / NaOH / methanol; diethyl ether / 1 h / Ambient temperature

4: 79 percent / imidazole / dimethylformamide / 15 h

5: 64 percent / 4A molecular sieves, I(sym-collidine)2ClO₄ / CH₂Cl₂ / 2 h / Ambient temperature

With 1H-imidazole; sodium hydroxide; iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; In methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja00199a027

upstream raw materials:

1,5-anhydro-3,6-di-O-benzoyl-2-deoxy-D-arabino-hex-1-enitol

(2R,3S,4R)-4-((2S,3S,4S,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-3-iodo-tetrahydro-pyran-2-yloxy)-3-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,4-dihydro-2H-pyran

3,4,6-tri-O-benzyl-D-glucal

6-O-Benzoyl-D-glucal

Downstream raw materials:

C₇₇H₁₀₁I₃O₂₀Si₂