(E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide

Base Information

• Chemical Name: (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide
• CAS No.: 1423715-37-0
• Molecular Formula: C₂₀H₂₃ClN₄O₄S
• Molecular Weight: 450.946

Synonyms:(E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide

Chemical Property of (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide

Chemical Property:

• Density: 1.39±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

Seclidemstat（SP-2577） >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide

There total 5 articles about (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.4%

5-chloro-2-hydroxyacetophenone (1450-74-4) + 3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide (1423715-36-9) → (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide (1423715-37-0)

Guidance literature:

With acetic acid; In methanol; at 120 ℃; for 0.5h; Microwave irradiation;

Reference yield:

3-((4-methylpiperazin-1-yl)sulfonyl)benzoic acid (380339-63-9) → (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide (1423715-37-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid / 70 °C

2: hydrazine / methanol / 8 h / 65 °C

3: acetic acid / methanol / 0.5 h / 120 °C / Microwave irradiation

With sulfuric acid; acetic acid; hydrazine; In methanol;

Reference yield:

methyl 3-((4-methylpiperazin-1-yl)sulfonyl)benzoate (1323817-07-7) → (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide (1423715-37-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine / methanol / 8 h / 65 °C

2: acetic acid / methanol / 0.5 h / 120 °C / Microwave irradiation

With acetic acid; hydrazine; In methanol;

upstream raw materials:

1-methyl-piperazine

3-((4-methylpiperazin-1-yl)sulfonyl)benzoic acid

methyl 3-((4-methylpiperazin-1-yl)sulfonyl)benzoate

5-chloro-2-hydroxyacetophenone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1423715-37-0 (E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide

Send

Send

Metric Ton KG G Pound L ML

Send

Send