N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea

Base Information

• Chemical Name: N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea
• CAS No.: 1256282-45-7
• Molecular Formula: C₂₅H₂₆N₂O₂S
• Molecular Weight: 418.56
• Mol file: 1256282-45-7.mol

Synonyms:N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea

Chemical Property of N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea

There total 1 articles about N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.5%

O-(4-vinylbenzyl)-L-tyrosinol (1229616-65-2) + phenyl isothiocyanate (103-72-0) → N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea (1256282-45-7)

Guidance literature:

In tetrahydrofuran; at 25 ℃;

DOI:10.1002/ejoc.201000981

Reference yield: 94.5%

N-{2-[(S)-4-(4'-vinylbenzyloxy)benzyl]hydroxyethyl}-N'-phenylthiourea (1256282-45-7) → (S)-[4-(4'-vinylbenzyloxy)benzyl]-2-phenylimino-2-oxazolidine (1256282-47-9)

Guidance literature:

With p-toluenesulfonyl chloride; sodium hydroxide; In tetrahydrofuran; at 25 ℃;

DOI:10.1002/ejoc.201000981

upstream raw materials:

O-(4-vinylbenzyl)-L-tyrosinol

phenyl isothiocyanate

Downstream raw materials:

(S)-[4-(4'-vinylbenzyloxy)benzyl]-2-phenylimino-2-oxazolidine