Technology Process of C43H53N5O12S
There total 12 articles about C43H53N5O12S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: hydrogenchloride / water / 16 h / 100 °C
1.2: 2 h / 5 °C / pH 8
2.1: bromine / chloroform / 1 h / 10 °C / Reflux
3.1: tert.-butylnitrite / N,N-dimethyl-formamide / 1 h / 60 °C
4.1: aluminum (III) chloride / carbon disulfide / 1.5 h / Reflux
5.1: pyridine hydrochloride / 2 h / 200 °C
6.1: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere
7.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene / 80 °C / Inert atmosphere
8.1: bromine; acetic acid / chloroform / 70 °C
9.1: caesium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
With
hydrogenchloride; tert.-butylnitrite; bromine; pyridine hydrochloride; sodium carbonate; caesium carbonate; acetic acid; triethylamine;
aluminum (III) chloride; tetrakis(triphenylphosphine) palladium(0);
In
carbon disulfide; dichloromethane; chloroform; water; N,N-dimethyl-formamide; toluene;
7.1: Suzuki Coupling;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: aluminum (III) chloride / carbon disulfide / 1.5 h / Reflux
2: pyridine hydrochloride / 2 h / 200 °C
3: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere
4: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene / 80 °C / Inert atmosphere
5: bromine; acetic acid / chloroform / 70 °C
6: caesium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
With
bromine; pyridine hydrochloride; sodium carbonate; caesium carbonate; acetic acid; triethylamine;
aluminum (III) chloride; tetrakis(triphenylphosphine) palladium(0);
In
carbon disulfide; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene;
4: Suzuki Coupling;