{(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

Base Information

Chemical Name:{(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol
CAS No.:410095-26-0
Molecular Formula:C₃₁H₅₀O₆Si
Molecular Weight:546.82
Hs Code.:

Synonyms:{(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

Suppliers and Price of {(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

There total 16 articles about {(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 410095-22-6
(2E,7E)-(5R,6S)-5-(4-Methoxy-benzyloxy)-8-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-6-triisopropylsilanyloxy-octa-2,7-dien-1-ol

: 410095-26-0
{(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

: {(2R,3R)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

Guidance literature:: With tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate;
DOI:10.1016/S0040-4039(01)02120-7

Reference yield:

: 302554-87-6
(S)-2-allyloxy-4-methyl-1-trityloxy-4-pentene

: 410095-26-0
{(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

Guidance literature:: Multi-step reaction with 8 steps

1: 95 percent / Grubbs' catalyst / CH₂Cl₂

2: 81 percent / TFA / methanol

3: 85 percent / DIAD; PPh₃

4: 45 percent / (NH₄)6Mo₇O₂₄; H₂O₂ / ethanol

5: KHMDS / 1,2-dimethoxy-ethane

6: 87 percent / NaOH / methanol / Heating

7: 85 percent / Red-Al / diethyl ether

8: 84 percent / (+)-DIPT; TBHP

With tert.-butylhydroperoxide; ammonium heptamolybdate; sodium hydroxide; L-(+)-diisopropyl tartrate; di-isopropyl azodicarboxylate; dihydrogen peroxide; potassium hexamethylsilazane; triphenylphosphine; sodium bis(2-methoxyethoxy)aluminium dihydride; trifluoroacetic acid; Grubbs catalyst first generation; In methanol; 1,2-dimethoxyethane; diethyl ether; ethanol; dichloromethane; 3: Mitsunobu coupling / 5: Julia/Kocienski coupling / 8: Sharpless epoxidation;
DOI:10.1016/S0040-4039(01)02120-7

Reference yield:

: 66335-71-5
(S)-4-methyl-1-trityloxymethyl-3,6-dihydro-2H-pyran

: 410095-26-0
{(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol

Guidance literature:: Multi-step reaction with 7 steps

1: 81 percent / TFA / methanol

2: 85 percent / DIAD; PPh₃

3: 45 percent / (NH₄)6Mo₇O₂₄; H₂O₂ / ethanol

4: KHMDS / 1,2-dimethoxy-ethane

5: 87 percent / NaOH / methanol / Heating

6: 85 percent / Red-Al / diethyl ether

7: 84 percent / (+)-DIPT; TBHP

With tert.-butylhydroperoxide; ammonium heptamolybdate; sodium hydroxide; L-(+)-diisopropyl tartrate; di-isopropyl azodicarboxylate; dihydrogen peroxide; potassium hexamethylsilazane; triphenylphosphine; sodium bis(2-methoxyethoxy)aluminium dihydride; trifluoroacetic acid; In methanol; 1,2-dimethoxyethane; diethyl ether; ethanol; 2: Mitsunobu coupling / 4: Julia/Kocienski coupling / 7: Sharpless epoxidation;
DOI:10.1016/S0040-4039(01)02120-7