N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide

Base Information

Chemical Name:N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide
CAS No.:1150100-55-2
Molecular Formula:C₂₅H₂₉FN₄O₃S
Molecular Weight:484.595
Hs Code.:

Synonyms:N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide

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Chemical Property of N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide

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Technology Process of N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide

There total 1 articles about N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 886506-63-4
N-(3-fluorophenyl)-4-piperidinamine

: 1150100-30-3
C₁₄H₁₄N₂O₄S

: 1150100-55-2
N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide

Guidance literature:: N-(3-fluorophenyl)-4-piperidinamine; C₁₄H₁₄N₂O₄S; With sodium tris(acetoxy)borohydride; acetic acid; In 1,1-dichloroethane; at 0 - 20 ℃; for 2.5h;

With sodium hydroxide; water; In 1,1-dichloroethane;

Reference yield:

: C₉H₆ClF₂NO₃

: 1150100-55-2
N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide

: 1150100-56-3
methyl 2,4-difluoro-5-({[(3-fluorophenyl)(1-{[2-methyl-6-({4-[(methylsulfonyl)amino]phenyl}oxy)-3-pyridinyl]methyl}-4-piperidinyl)amino]carbonyl}amino)benzoate

Guidance literature:: C₉H₆ClF₂NO₃; N-(4-{[5-({4-[(3-fluorophenyl)amino]-1-piperidinyl}methyl)-6-methyl-2-pyridinyl]oxy}phenyl)methanesulfonamide; In dichloromethane; at 20 ℃; for 18h;

With sodium hydrogencarbonate; In dichloromethane; water;