(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

Base Information

Chemical Name:(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone
CAS No.:943060-97-7
Molecular Formula:C₂₇H₃₇NO₄
Molecular Weight:439.595
Hs Code.:

Synonyms:(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

Suppliers and Price of (4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

There total 6 articles about (4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 17049-49-9
octylmagnesium bromide

: 943060-96-6
(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-formyl-2-oxazolidinone

: 943060-97-7
(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

Guidance literature:: octylmagnesium bromide; With cerium(III) chloride; In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h;

(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-formyl-2-oxazolidinone; In tetrahydrofuran; diethyl ether; at -78 - 0 ℃; for 6h; Further stages.;
DOI:10.1016/j.tetasy.2007.03.029

Reference yield:

: 943060-94-4
(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-(hydroxymethyl)-2-oxazolidinone

: 943060-97-7
(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

Guidance literature:: Multi-step reaction with 2 steps

1.1: 90 percent / Dess-Martin periodinane / CH₂Cl₂ / 3 h / 20 °C

2.1: CeCl₃ / tetrahydrofuran; diethyl ether / 1 h / -78 °C

2.2: 56 percent / tetrahydrofuran; diethyl ether / 6 h / -78 - 0 °C

With cerium(III) chloride; Dess-Martin periodane; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1016/j.tetasy.2007.03.029

Reference yield:

: 80885-30-9,81028-03-7,69152-88-1
(E)-4-(benzyloxy)-2-buten-1-ol

: 943060-97-7
(4S,5S)-3-benzyl-4-(benzyloxymethyl)-5-[(1R)-1-(hydroxynonyl)]-2-oxazolidinone

Guidance literature:: Multi-step reaction with 4 steps

1.1: (-)-diethyl tartrate; Ti(Oi-Pr)4 / CH₂Cl₂ / 0.5 h / -23 °C

1.2: t-BuOOH / CH₂Cl₂; decane / 72 h / -23 °C

1.3: dimethyl sulfide / CH₂Cl₂; decane / 3 h / -23 °C

2.1: Ti(Oi-Pr)4 / CH₂Cl₂; decane / 36 h / 20 °C

2.2: K₂CO₃ / tetrahydrofuran / 18 h / 20 °C

2.3: 893 mg / KOH / methanol / 5 h / 20 °C

3.1: 90 percent / Dess-Martin periodinane / CH₂Cl₂ / 3 h / 20 °C

4.1: CeCl₃ / tetrahydrofuran; diethyl ether / 1 h / -78 °C

4.2: 56 percent / tetrahydrofuran; diethyl ether / 6 h / -78 - 0 °C

With titanium(IV) isopropylate; cerium(III) chloride; Dess-Martin periodane; (-)-diethyl tartrate; In tetrahydrofuran; diethyl ether; decane; dichloromethane; 1.1: Sharpless asymmetric epoxidation;
DOI:10.1016/j.tetasy.2007.03.029