rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate

Base Information

• Chemical Name: rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate
• CAS No.: 112489-43-7
• Molecular Formula: C₄₈H₄₉Br₂N₆O₁₆P₃
• Molecular Weight: 1218.68
• Mol file: 112489-43-7.mol

Synonyms:rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate

Chemical Property of rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate

There total 20 articles about rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,7-dibromo-9H-xanthen-9-one (40102-85-0) → hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-D-myo-inositol 1,4,5-triphosphate (112489-43-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 69 percent / diethyl ether

2: acetyl chloride / benzene / Ambient temperature

4: 1H-tetrazole / CH₂Cl₂ / 1 h / Ambient temperature

5: t-butyl hydroperoxide, 2,6-lutidine / CH₂Cl₂; tetrahydrofuran; H₂O / 16 h / Ambient temperature

With 2,6-dimethylpyridine; 1H-tetrazole; tert.-butylhydroperoxide; acetyl chloride; In tetrahydrofuran; diethyl ether; dichloromethane; water; benzene;

DOI:10.1016/S0040-4039(00)96111-2

Reference yield:

2,7-dibromo-9H-xanthen-9-one (40102-85-0) → rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate (112489-43-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 69 percent / diethyl ether

2: acetyl chloride / benzene / Ambient temperature

4: 1H- tetrazole / CH₂Cl₂ / 1 h / Ambient temperature

5: t-butyl hydroperoxide, 2,6-lutidine / CH₂Cl₂; tetrahydrofuran; H₂O / 16 h / Ambient temperature

With 2,6-dimethylpyridine; 1H-tetrazole; tert.-butylhydroperoxide; acetyl chloride; In tetrahydrofuran; diethyl ether; dichloromethane; water; benzene;

DOI:10.1016/S0040-4039(00)96111-2

Reference yield:

1,1-dimethoxycyclopentane (931-94-2) → hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-D-myo-inositol 1,4,5-triphosphate (112489-43-7)

Guidance literature:

Multi-step reaction with 5 steps

1: toluene-p-sulphonic acid / acetonitrile

2: Na / liquid ammonia; tetrahydrofuran

4: 1H-tetrazole / CH₂Cl₂ / 1 h / Ambient temperature

5: t-butyl hydroperoxide, 2,6-lutidine / CH₂Cl₂; tetrahydrofuran; H₂O / 16 h / Ambient temperature

With 2,6-dimethylpyridine; 1H-tetrazole; tert.-butylhydroperoxide; sodium; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; ammonia; water; acetonitrile;

DOI:10.1016/S0040-4039(00)96111-2

upstream raw materials:

2,3-O-cyclopentylidene-myo-inositol

1,1-dimethoxycyclopentane

1,4,5,6-tetra-O-benzyl-myo-inositol

2,7-dibromo-9H-xanthen-9-one

Downstream raw materials:

C₃₀H₃₁Br₂O₁₆P₃

C₃₀H₃₁Br₂O₁₆P₃

Refernces