C₆₈H₈₄INO₈

Base Information

• Chemical Name: C₆₈H₈₄INO₈
• CAS No.: 1558035-07-6
• Molecular Formula: C₆₈H₈₄INO₈
• Molecular Weight: 1170.32
• Mol file: 1558035-07-6.mol

Synonyms:C₆₈H₈₄INO₈

Chemical Property of C₆₈H₈₄INO₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₈H₈₄INO₈

There total 16 articles about C₆₈H₈₄INO₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.9%

C69H87NO7S (1558035-06-5) → C68H84INO8 (1558035-07-6)

Guidance literature:

With iodonium dicollidine perchlorate; In dichloromethane; at 20 ℃; for 4h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ol5002686

Reference yield:

1-(3',4',6'-tri-O-benzyl-α-D-galactopyranosyl)-2-propene (271246-08-3) → C68H84INO8 (1558035-07-6)

Guidance literature:

Multi-step reaction with 8 steps

1.1: pyridine; dmap / 16 h / 20 °C / Inert atmosphere

2.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere

2.2: 1 h / 20 °C / Inert atmosphere

3.1: ethene; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / 40 °C

4.1: diisobutylaluminium hydride / dichloromethane; hexane / 3 h / -78 - 20 °C / Inert atmosphere

5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3 h / 0 - 20 °C / Inert atmosphere

6.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 0.5 h / 0 °C / Inert atmosphere

7.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

7.2: 3 h / 20 °C / Inert atmosphere

7.3: 1 h / 20 °C / Inert atmosphere

8.1: iodonium dicollidine perchlorate / dichloromethane / 4 h / 20 °C / Inert atmosphere

With pyridine; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; dmap; ethene; 2,4,6-trichlorobenzoyl chloride; sodium hydride; diisobutylaluminium hydride; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;

DOI:10.1021/ol5002686

Reference yield:

C38H38O8 (1558034-99-3) → C68H84INO8 (1558035-07-6)

Guidance literature:

Multi-step reaction with 7 steps

1.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: ethene; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / 40 °C

3.1: diisobutylaluminium hydride / dichloromethane; hexane / 3 h / -78 - 20 °C / Inert atmosphere

4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3 h / 0 - 20 °C / Inert atmosphere

5.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 0.5 h / 0 °C / Inert atmosphere

6.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

6.2: 3 h / 20 °C / Inert atmosphere

6.3: 1 h / 20 °C / Inert atmosphere

7.1: iodonium dicollidine perchlorate / dichloromethane / 4 h / 20 °C / Inert atmosphere

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; ethene; 2,4,6-trichlorobenzoyl chloride; sodium hydride; diisobutylaluminium hydride; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;

DOI:10.1021/ol5002686

upstream raw materials:

1-(3',4',6'-tri-O-benzyl-α-D-galactopyranosyl)-2-propene

C₃₈H₃₈O₈

C₆₄H₈₀O₁₀

C₆₂H₇₆O₁₀

Downstream raw materials:

C₆₈H₈₅NO₈

C₆₇H₈₇NO₇