2-Bromo-1-(3-bromo-4-fluorophenyl)ethanone

Base Information

• Chemical Name: 2-Bromo-1-(3-bromo-4-fluorophenyl)ethanone
• CAS No.: 435273-49-7
• Molecular Formula: C8H5 Br2 F O
• Molecular Weight: 295.934
• Hs Code.: 2914700090
• European Community (EC) Number: 623-814-3
• DSSTox Substance ID: DTXSID40382291
• Wikidata: Q82173607
• Mol file: 435273-49-7.mol

Synonyms:435273-49-7;2-bromo-1-(3-bromo-4-fluorophenyl)ethanone;2,3'-Dibromo-4'-fluoroacetophenone;2,3'-Dibromo-4-fluoroacetophenone;3'-Bromo-4'-fluorophenacyl bromide;SCHEMBL3162903;3-Bromo-4-fluorophenacyl bromide;DTXSID40382291;NVCNENXQUDVWRV-UHFFFAOYSA-N;MFCD07368759;AKOS009158095;PS-9974;2,3'-Dibromo-4'-fluoroacetophenone, 97%;CS-0186563;2-bromo-1-(3-bromo-4-fluorophenyl) ethanone;2-Bromo-1-(3-bromo-4-fluoro-phenyl)-ethanone;F20940;2,3 inverted exclamation marka-Dibromo-4 inverted exclamation marka-fluoroacetophenone

Chemical Property of 2-Bromo-1-(3-bromo-4-fluorophenyl)ethanone

Chemical Property:

• Vapor Pressure: 0.00114mmHg at 25°C
• Melting Point: 48-52 °C
• Refractive Index: 1.597
• Boiling Point: 300.2°C at 760 mmHg
• Flash Point: 110 °C
• PSA: 17.07000
• Density: 2.042g/cm³
• LogP: 3.16580
• Storage Temp.: 2-8°C
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 295.86707
• Heavy Atom Count: 12
• Complexity: 174

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Bromo-1-(3-bromo-4-fluorophenyl)ethanone ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C(=O)CBr)Br)F

Technology Process of 2-Bromo-1-(3-bromo-4-fluorophenyl)ethanone

There total 2 articles about 2-Bromo-1-(3-bromo-4-fluorophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

→ 2-bromo-1-(3-bromo-4-fluoro-phenyl)-ethanone (435273-49-7)

Guidance literature:

With bromine; acetic acid; Irradiation;

Reference yield:

4-fluoro-3-bromoacetophenone (1007-15-4) → 2-bromo-1-(3-bromo-4-fluoro-phenyl)-ethanone (435273-49-7)

Guidance literature:

With bromine; In dichloromethane; acetic acid; at 10 ℃; for 0.25h;

Reference yield: 95.0%

2-bromo-1-(3-bromo-4-fluoro-phenyl)-ethanone (435273-49-7) + C17H25ClF2O3Si → 2-(3-bromo-4-fluorophenyl)-2-oxoethyl 3-(4-((tert-butyl-dimethylsilyl)oxy)-1,1-difluorobutyl)-4-chlorobenzoate

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; acetonitrile; at 0 - 20 ℃;

upstream raw materials:

4-fluoro-3-bromoacetophenone

Downstream raw materials:

C₁₀H₇BrFNS

C₉H₈BrFO