Technology Process of C20H20ClN3O2
There total 4 articles about C20H20ClN3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-chloro-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine;
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 5 ℃;
for 0.333333h;
Inert atmosphere;
cyclopropylcarbinyl bromide;
In
N,N-dimethyl-formamide; mineral oil;
at 5 - 20 ℃;
for 1.83333h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,2-dimethoxyethane / 5 h / Inert atmosphere; Reflux
2.1: trichlorophosphate / 0.67 h / 80 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 5 °C / Inert atmosphere
3.2: 1.83 h / 5 - 20 °C
With
sodium hydride; sodium t-butanolate; trichlorophosphate;
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
1,2-dimethoxyethane; N,N-dimethyl-formamide; mineral oil;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,2-dimethoxyethane / 5 h / Inert atmosphere; Reflux
2.1: trichlorophosphate / 0.67 h / 80 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 5 °C / Inert atmosphere
3.2: 1.83 h / 5 - 20 °C
With
sodium hydride; sodium t-butanolate; trichlorophosphate;
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
1,2-dimethoxyethane; N,N-dimethyl-formamide; mineral oil;
